Effect of Follicular Flushing in Patients With Mono-follicular Growth Undergoing In Vitro Fertilization
NCT ID: NCT03831542
Last Updated: 2019-05-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
71 participants
OBSERVATIONAL
2019-02-19
2019-05-06
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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direct aspiration group
Transvaginal ultrasound-guided oocyte retrieval was performed 36 hours after ovulation trigger. A 17-gauge double lumen needle will be used to aspirate a single follicle without flushing. If an oocyte is obtained, the subject will be assigned to group 1. If not, operator will proceed with follicular flushing.
direct follicular aspiration
direct follicular aspiration
flushing group
If an oocyte is not obtained with direct aspiration, operator will proceed to follicular flushing and the subject will be assigned to group 2 if an oocyte is obtained following follicular flushing.
follicular flushing
follicular flushing
Interventions
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direct follicular aspiration
direct follicular aspiration
follicular flushing
follicular flushing
Eligibility Criteria
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Inclusion Criteria
* primary infertility
* diminished ovarian reserve with single mature follicle on the day of oocyte retrieval
Exclusion Criteria
* presence of endometriosis/endometrioma(s)
* Absence of cumulus oocyte complex following oocyte retrieval
* Severe male factor infertility
* Pre-implantation genetic screening cycles
18 Years
40 Years
FEMALE
Yes
Sponsors
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Centrum Clinic IVF Center
OTHER
Responsible Party
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Emre Göksan Pabuçcu
Emre G. Pabuccu, Assoc. Prof.
Principal Investigators
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Emre Pabuccu, MD
Role: STUDY_DIRECTOR
Centrum Clinic IVF Center
Locations
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Centrum Clinic IVF Center
Ankara, , Turkey (Türkiye)
Countries
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References
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von Horn K, Depenbusch M, Schultze-Mosgau A, Griesinger G. Randomized, open trial comparing a modified double-lumen needle follicular flushing system with a single-lumen aspiration needle in IVF patients with poor ovarian response. Hum Reprod. 2017 Apr 1;32(4):832-835. doi: 10.1093/humrep/dex019.
Haydardedeoglu B, Gjemalaj F, Aytac PC, Kilicdag EB. Direct aspiration versus follicular flushing in poor responders undergoing intracytoplasmic sperm injection: a randomised controlled trial. BJOG. 2017 Jul;124(8):1190-1196. doi: 10.1111/1471-0528.14629. Epub 2017 May 2.
Other Identifiers
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1
Identifier Type: -
Identifier Source: org_study_id
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