Local Injection of PRP During Repair of Disrupted Surgical Wounds

NCT ID: NCT03781882

Last Updated: 2020-05-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

220 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-01-01

Study Completion Date

2020-03-31

Brief Summary

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Patients with disrupted wounds will either managed as usual or managed by Platelet rich plasma local infiltration in the wound edges

Detailed Description

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The patients with disrupted surgical wounds will be cleansed, debrided and closed with infiltration of platelet rich plasma in one group and the other group will be closed without infiltration of Platelet rich plasma

Conditions

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Role of Platelet Rich Plasma in Wound Healing

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

All cases with disrupted surgical wounds admitted at Obstetrics and Gynecology departments
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants
Patients were not allowed to know allocations

Study Groups

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Intervention group

All patients in this group will be manged as usual with infiltration of platelet rich plasma in thee wound edges during closure of the wounds

Group Type ACTIVE_COMPARATOR

Platelet rich plasma infiltration in the wound edges

Intervention Type PROCEDURE

platelet rich plasma will be injected in the wound edges

Control group

All patients in this group will be managed by repair of wounds without infiltration of platelet rich plasma

Group Type ACTIVE_COMPARATOR

Closure of wound without platelet rich plasma infiltration

Intervention Type PROCEDURE

No infiltration of platelet rich plasma is done

Interventions

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Platelet rich plasma infiltration in the wound edges

platelet rich plasma will be injected in the wound edges

Intervention Type PROCEDURE

Closure of wound without platelet rich plasma infiltration

No infiltration of platelet rich plasma is done

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Disrupted surgical wounds after cesarean sections and other gynecological operations
* Body mass index 18-25
* Hemoglobin \> 10.5gm/dl
* Albumin \>3.5gm/dl

Exclusion Criteria

* Medical disorders asDiabetes mellitus (DM), Liver disease or systemic lupus erythymatosus (SLE)
* Patient on corticosteriod therapy
* Thrombocytopenia
* Coagulation disorders
Minimum Eligible Age

20 Years

Maximum Eligible Age

50 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Tanta University

OTHER

Sponsor Role lead

Responsible Party

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Ayman S Dawood, MD

Lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Ayman Shehata Dawood

Tanta, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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PRP surgical wounds

Identifier Type: -

Identifier Source: org_study_id

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