Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
25 participants
OBSERVATIONAL
2018-11-20
2024-08-31
Brief Summary
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Detailed Description
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FDG PET/CT, with appropriate suppression protocol including high-fat-low-carbohydrate diet, fasting, and IV heparin, can be use to detect myocardial inflammation. It is frequently used for the diagnosis of inflammation in cardiac sarcoidosis. After the initial inflammatory phase, inflammation resolves and fibrosis can seen. Resting perfusion imaging will allow identification of fibrosis. The combination of FDG PET/CT and rest perfusion imaging could allow detection of the various phases of myocarditis; inflammation and fibrosis.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Interventions
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FDG PET/CT
FDG PET CT imaging with rest perfusion imaging
Eligibility Criteria
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Inclusion Criteria
2. Clinical suspicion of myocarditis due to findings such as:
1. Symptoms and signs of myocarditis such as dyspnea, orthopnea, palpitation, and chest pain, without other identifiable cause
2. New onset of cardiovascular symptoms with recent history of viral disease or previous myocarditis
3. Unexplained new onset of left ventricular dysfunction
4. Unexplained elevated troponin
5. Magnetic resonance imaging findings suggestive of myocarditis, such as late gadolinium enhancement and edema
6. Biopsy findings compatible with myocarditis
3. Women of childbearing potential must have a negative urine or blood pregnancy test
4. Capable of giving informed consent and the consent must be obtained prior to any study related procedures
5. Subject's with body mass index inferior or equal to 45 kg/m2
Exclusion Criteria
2. Claustrophobia or inability to lie still in a supine position for imaging purposes
3. Unwillingness or inability to provide informed consent
18 Years
ALL
No
Sponsors
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Montreal Heart Institute
OTHER
Responsible Party
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Matthieu Pelletier-Galarneau, MD MSc
Adjunct Professor of Clinic
Locations
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Matthieu Pelletier-Galarneau
Montreal, Quebec, Canada
Countries
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Other Identifiers
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2019-2395
Identifier Type: -
Identifier Source: org_study_id
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