Neurobehavioral Moderators of Post-traumatic Disease Trajectories

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

173 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-01-20

Study Completion Date

2020-03-11

Brief Summary

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The research goal is to uncover the neurocognitive moderators of PTSD trajectories, by documenting clinical symptoms, cognitive functioning, and brain structure and function, one-, six- and fourteen months following a traumatic event, in a large population of survivors at initial high risk for PTSD.

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Detailed Description

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Conditions

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PTSD Trauma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Age 18 - 65 years
* Able to read and comprehend Hebrew
* Arrived in the ER because of one of the following: car accidents, terrorist attacks, work accidents, home accidents, burns, physical assault, large-scale disaster.

Exclusion Criteria

* Individuals with known claustrophobia
* Individuals with history of substance abuse
* Individuals with current or past psychotic or bipolar I disorder
* Individuals with chronic PTSD at the time of the current trauma
* Individuals on psychotropic medication or recreational drugs in the week that precedes the MRI
* Individuals with hearing problems
* Individuals with head trauma with coma exceeding 30 minutes
* Individuals which can't perform MRI due to safety reasons (e.g. irremovable metals in their body)

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No