Research on the Effects of Combined Neurostimulation Protocols on Stress
NCT ID: NCT03722095
Last Updated: 2021-11-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
74 participants
INTERVENTIONAL
2018-10-29
2020-10-31
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
CROSSOVER
OTHER
TRIPLE
Study Groups
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active tDCS + active iTBS
Participants will receive 20 minutes of active tDCS, during the last 7 minutes active iTBS will be applied.
active tDCS
A current of 2 milliampère (mA) through electrodes of 5x5cm.
iTBS
54 cycles with 10 bursts of 3 pulses, train duration of 2 seconds and intertrain intervals of 6 seconds, results in 1620 pulses at 110% resting motor threshold.
sham tDCS + active iTBS
Participants will receive 20 minutes of sham tDCS, during the last 7 minutes active iTBS will be applied.
sham tDCS
Similar set-up as in the active tDCS, but stimulation is too short to cause any effects.
iTBS
54 cycles with 10 bursts of 3 pulses, train duration of 2 seconds and intertrain intervals of 6 seconds, results in 1620 pulses at 110% resting motor threshold.
Interventions
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active tDCS
A current of 2 milliampère (mA) through electrodes of 5x5cm.
sham tDCS
Similar set-up as in the active tDCS, but stimulation is too short to cause any effects.
iTBS
54 cycles with 10 bursts of 3 pulses, train duration of 2 seconds and intertrain intervals of 6 seconds, results in 1620 pulses at 110% resting motor threshold.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Usage of psychotropic medication
* Any or cardiovascular neurological condition
* Personal or family history of epilepsy or other neurological disorders
* Unstable medical condition, as well as chronic pain conditions, (such as fibromyalgia) or increased blood pressure
* Eye disease(s)
* Current substance abuse
* Inner ear prosthesis
* Any implanted electronic device susceptible for magnetic field radiation (e.g. pacemaker)
* Any implanted metal device in the head region
* Metal objects or magnetic objects in the brain or around the head (only removable earrings \& piercing are allowed)
* Recent neurosurgical interventions
* Pregnancy
* Skin problems in the head region
* Recent fractures or wounds on the hand
18 Years
45 Years
ALL
Yes
Sponsors
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University Hospital, Ghent
OTHER
University Ghent
OTHER
Responsible Party
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Principal Investigators
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Chris Baeken, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Ghent University, University Hospital Ghent
Marie-Anne Vanderhasselt, PhD
Role: PRINCIPAL_INVESTIGATOR
Ghent University, University Hospital Ghent
Stefaan Van Damme, PhD
Role: PRINCIPAL_INVESTIGATOR
University Ghent
Locations
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University Hospital Ghent
Ghent, , Belgium
Countries
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Other Identifiers
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EC/2018/0866
Identifier Type: -
Identifier Source: org_study_id