Effects of Gene Polymorphism After Transcranial Cranial Direct Current Stimulation on the Corticobulbar Excitability

NCT ID: NCT03712150

Last Updated: 2019-11-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-11-10

Study Completion Date

2019-08-08

Brief Summary

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This study aims to examine the effects of transcranial direct current stimulation at corticobulbar excitability in individuals with different gene polymorphism.

Detailed Description

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The effects of TDCS on corticobulbar excitability of the brain after inhibitory pre-conditioning will be compared in patients with different BDNF phenotypes

Conditions

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Healthy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Healthy

Healthy adults

\- Participants will receive single session of tdcs after application

tdcs

Intervention Type DEVICE

application of optimised parameters of tDCS (anodal stimulation, 1.5 mA, 10 min) over the unconditioned hemisphere reverses the brain and behavioural consequences of inhibitory pre-conditioning

Interventions

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tdcs

application of optimised parameters of tDCS (anodal stimulation, 1.5 mA, 10 min) over the unconditioned hemisphere reverses the brain and behavioural consequences of inhibitory pre-conditioning

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age 19-40 years
* Informed consent

Exclusion Criteria

* History of epilepsy
* Presence of cardiac pacemaker
* previous brain surgery
* previous swallowing problems
* current use of medication which acts on the central nervous system
* presence of implanted metal intracranially
Minimum Eligible Age

19 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The Catholic University of Korea

OTHER

Sponsor Role lead

Responsible Party

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Sun Im

Sun Im, Assistant Professor, The Catholic University of Korea

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Sun Im, MD PhD

Role: PRINCIPAL_INVESTIGATOR

The Catholic University of Korea

Locations

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Department of Rehabilitation Medicine

Bucheon-si, Bucheonshi, South Korea

Site Status

Department of Rehabilitation Medicine Bucheon St Mary's Hospital, Catholic University of Korea, College of Medicine

Bucheon-si, Kyounggido, South Korea

Site Status

Countries

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South Korea

Other Identifiers

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HC18TNSV0061

Identifier Type: -

Identifier Source: org_study_id

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