Happy Smooth Study

NCT ID: NCT03710551

Last Updated: 2021-02-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

140 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-09-26

Study Completion Date

2019-07-21

Brief Summary

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The purpose of this study is to evaluate the stool composition and GI tolerance of an experimental formula with a new fat blend plus L. reuteri vs control formula.

Detailed Description

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Double-blind, randomized, controlled clinical trial. The purpose of this study is to evaluate the stool composition and GI tolerance of 140 healthy, term infants fed with an infant formula with a new fat blend plus L. reuteri vs a standard infant formula. All enrolled infants will participate in the trial for approximately 71 days.

Conditions

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Infant Term Birth

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Experimental Infant Formula

Experimental Infant Formula with a new fat blend plus L. reuteri

Group Type EXPERIMENTAL

Experimental Infant Formula

Intervention Type OTHER

Standard bovine milk-based infant formula with a new fat blend plus L. reuteri, fed ad libitum

Standard Infant Formula

Standard bovine milk-based infant formula.

Group Type ACTIVE_COMPARATOR

Standard Infant Formula

Intervention Type OTHER

Standard bovine milk-based infant formula, fed ad libitum

Interventions

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Experimental Infant Formula

Standard bovine milk-based infant formula with a new fat blend plus L. reuteri, fed ad libitum

Intervention Type OTHER

Standard Infant Formula

Standard bovine milk-based infant formula, fed ad libitum

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Written Informed Consent
* Infants whose parents/LAR have reached the legal age of majority in the Philippines
* Infants whose parent(s)/LAR are willing and able to comply with scheduled visits, and the requirements of the study protocol
* Infants whose parent(s)/LAR are able to be contacted directly by telephone throughout the study
* Healthy term, singleton infant at birth
* Between 21 to 28 days post-natal age at enrollment visit
* Weight-for-age ≥ 5th and ≤ 95th percentile according to World Health Organization growth tables/charts
* Infants of parent(s)/LAR who have previously made the decision to formula feed their infant at the time of enrollment

Exclusion Criteria

* Infants with conditions requiring infant feedings other than those specified in the protocol
* Infants receiving complementary foods or liquids
* Infants who have a medical condition or history that could increase the risk associated with study participation or interfere with the interpretation of study results
* Infants who are presently receiving or have received medications that could interfere with the interpretation of the study results
Minimum Eligible Age

21 Days

Maximum Eligible Age

28 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Société des Produits Nestlé (SPN)

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Elvira M Estorninos

Role: PRINCIPAL_INVESTIGATOR

University of Alberta

Locations

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Asian Hospital and Medical Center

City of Muntinlupa, , Philippines

Site Status

Countries

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Philippines

Other Identifiers

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16.28.INF

Identifier Type: -

Identifier Source: org_study_id

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