Gastrointestinal Tolerance And General Health Status Of Healthy Term Infants Fed A New Infant Formula

NCT ID: NCT01370967

Last Updated: 2013-12-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

460 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-07-31

Study Completion Date

2013-07-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to assess stool consistency, in combination with additional health-related parameters including gastrointestinal tolerance and health-related quality of life, in a large sample of Chinese infants. We will also assess the timing of, frequency, and reasons for changes in the choice of formula or method of feeding among infants in this sample, as well as incidence of common infant illness and associated healthcare usage. Anthropometric measures and the frequency and duration of physician- and parent-reported gastrointestinal and other adverse events will be evaluated.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Parents / legally acceptable representatives of eligible infants will be invited to volunteer.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Healthy

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

infant term birth human milk infant formula breast feeding bottle feeding gastrointestinal tract quality of life infant development

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Study formula-fed only

Study formula feeding

Intervention Type OTHER

Infants who are exclusively fed the new study formula at time of enrollment

Human milk-fed only

Human milk feeding

Intervention Type OTHER

Infants who are exclusively fed human milk at time of enrollment

Mixed-fed using study formula only

Mixed feeding

Intervention Type OTHER

Infants who are exclusively fed human milk and the new study formula at time of enrollment

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Study formula feeding

Infants who are exclusively fed the new study formula at time of enrollment

Intervention Type OTHER

Human milk feeding

Infants who are exclusively fed human milk at time of enrollment

Intervention Type OTHER

Mixed feeding

Infants who are exclusively fed human milk and the new study formula at time of enrollment

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Healthy, term (37-42 weeks gestation), singleton infant at birth.
* Post-natal age between 35 and 49 days (date of birth = day 0) at time of study entry.
* At enrollment, weight-for-age ≥ 5th and ≤ 95th percentile according to World Health Organization growth tables / charts.

Exclusion Criteria

* Infants who are consuming any types/brands of formula other than the new study formula (either exclusively or in a mixed feeding regimen) at time of study enrollment.
* Suspected or documented severe acute or chronic medical or psychiatric condition or laboratory abnormality that may increase the risk associated with study participation or may interfere with the interpretation of study results, and in the judgment of the investigator, would make the infant inappropriate for entry into the study.
Minimum Eligible Age

35 Days

Maximum Eligible Age

49 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Société des Produits Nestlé (SPN)

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

The 306th Hospital of PLA

Chaoyang District, Beijing Municipality, China

Site Status

Beijing Haidian Maternal&Child Health Hospital

Haidian District, Beijing Municipality, China

Site Status

Children's Hospital of Chongqing Medical University

Yuzhong, Chongqing Municipality, China

Site Status

Dongguan People's Hospital

Dongguan, Guangdong, China

Site Status

The First Affiliated Hospital, Sun Yat-Sen University

Guangzhou, Guangdong, China

Site Status

Guangzhou Women and Children's Medical Center

Guangzhou, Guangdong, China

Site Status

Nanfang Hospital of Southern Medical University

Guangzhou, Guangdong, China

Site Status

The Third Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, China

Site Status

Zhu Jiang Hospital of Southern Medical University

Guangzhou, Guangdong, China

Site Status

Shantou Central Hospital

Shantou, Guangdong, China

Site Status

Zhongshan Bo'ai Hospital

Zhongshan, Guangdong, China

Site Status

Changsha Hospital for Maternal&Child Health Care

Changsha, Hunan, China

Site Status

Maternity and Child Health Care Hospital in Jiangsu Province

Nanjing, Jiangsu, China

Site Status

Nanjing Maternity and Child Health Care Hospital

Nanjing, Jiangsu, China

Site Status

Suzhou Municipal Hospital

Suzhou, Jiangsu, China

Site Status

Chengdu Women & Children Center Hospital

Chengdu, Sichuan, China

Site Status

West China Second University Hospital, SCU

Chengdu, Sichuan, China

Site Status

Tianjin First Center Hospital

Nankai, Tianjin Municipality, China

Site Status

Hangzhou First People's Hospital

Hangzhou, Zhejiang, China

Site Status

Ningbo Yinzhou People's Hospital

Ningbo, Zhejiang, China

Site Status

Beijing Obstetrics Gynecology Hospital

Beijing, , China

Site Status

Peking University First Hospital

Beijing, , China

Site Status

Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine

Shanghai, , China

Site Status

Children's Hospital of Fudan University

Shanghai, , China

Site Status

Countries

Review the countries where the study has at least one active or historical site.

China

References

Explore related publications, articles, or registry entries linked to this study.

Hays NP, Mao M, Zhang L, Ge J, Northington R, Yao M, Volger S. Infant feeding and health-related quality of life in healthy Chinese infants: results from a prospective, observational cohort study. Health Qual Life Outcomes. 2016 Aug 8;14(1):116. doi: 10.1186/s12955-016-0518-3.

Reference Type DERIVED
PMID: 27502768 (View on PubMed)

Related Links

Access external resources that provide additional context or updates about the study.

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

B3611002

Identifier Type: -

Identifier Source: org_study_id