Feeding Intolerance in Formula-Fed Infants

NCT ID: NCT02028156

Last Updated: 2014-11-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

3 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-01-31

Study Completion Date

2014-08-31

Brief Summary

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This is a non-randomized, single-group, multi-center, two phased study to evaluate formula intolerance.

Detailed Description

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Conditions

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Feeding Intolerance

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Blinding Strategy

NONE

Study Groups

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Partially Hydrolyzed Infant Formula

Fed ad lib.

Group Type EXPERIMENTAL

Partially Hydrolyzed Infant Formula

Intervention Type OTHER

Commercially available infant formula

Interventions

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Partially Hydrolyzed Infant Formula

Commercially available infant formula

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Singleton full term birth with birth weight of \> 2500g.
* Infant between 0 and 60 days of age.
* Discontinuation of medications that might affect gastrointestinal (GI) tolerance.
* Infant is exclusively formula-fed a full-lactose, intact cow milk protein-based infant formula (CMF) for less than 7 days prior to enrollment.


* Infant was fed according to protocol in Stage 1 of the study.
* Infant was identified as being fussy using the Intolerance Assessment Tool in Stage 1.

Exclusion Criteria

* Chromosomal or major congenital anomalies.
* Suspected or known metabolic or physical diseases affecting infant feeding and/or metabolism.
* Hospitalization, other than for delivery, prior to enrollment.
* Severe uncontrolled eczema, visible bloody stools or milk protein allergy prior to enrollment.
* More than 1 substitution of an infant formula other than full-lactose, intact cow milk formula (CMF) since birth.
* Use of a prokinetic drug within 7 days before enrollment.


* Infant's intolerance symptom was caused by another reason, for example known infection/illness, food allergy, or response to vaccination(s).
* Infant has immunization(s) within 3 days of enrollment in Stage 2.
Maximum Eligible Age

60 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Abbott Nutrition

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Shirley Li, MD

Role: STUDY_CHAIR

Abbott Nutrition China

Locations

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Guangdong Women and Children Hospital

Guangzhou, Guangdong, China

Site Status

Nanjing Maternity and Child Health Care Hospital

Nanjing, Jiangsu, China

Site Status

Xin Hua Hospital

Shanghai, , China

Site Status

Countries

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China

Other Identifiers

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DA06

Identifier Type: -

Identifier Source: org_study_id