China Health Big Data

NCT ID: NCT03699228

Last Updated: 2025-08-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

30000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-12-01

Study Completion Date

2026-12-31

Brief Summary

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In this nationwide multi center study the investigators combine the low dose chest CT scan data with QCT technology, to measure the BMD of spine, VAT and liver fat in the health check subjects. The aim of this study is to evaluate the performance of QCT in the health check field, and further to evaluate the prevalence of osteoporosis, obesity and liver steatosis in health check population across China.

Detailed Description

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Low dose Chest CT scan is the standard for lung cancer in the health check center in China. Quantitative computed tomography (QCT) is utilizing the CT raw data to measure the bone mineral density (BMD), the visceral fat (VAT) and liver fat content in human, which can be widely used in the diagnosis of osteoporosis, the assessment of obesity and liver steatosis. In this nationwide multi center study the investigators combine the low dose chest CT scan data with QCT technology, to measure the BMD of spine, VAT and liver fat in the health check subjects. This study is to evaluate the performance of QCT in the health check field, and further to evaluate the prevalence of osteoporosis, obesity and liver steatosis in health check population across China.

Conditions

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Osteoporosis Obesity Liver Steatoses

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

health check subjects 30-90 years old low dose chest CT scan

Exclusion Criteria

pregnant women metal implant in the CT scan area
Minimum Eligible Age

30 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Chinese PLA General Hospital

OTHER

Sponsor Role collaborator

Ruijin Hospital

OTHER

Sponsor Role collaborator

Huashan Hospital

OTHER

Sponsor Role collaborator

Henan Provincial People's Hospital

OTHER

Sponsor Role collaborator

The Affiliated Hospital Of Guizhou Medical University

OTHER

Sponsor Role collaborator

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

OTHER

Sponsor Role collaborator

The First Affiliated Hospital of Zhengzhou University

OTHER

Sponsor Role collaborator

First Affiliated Hospital Xi'an Jiaotong University

OTHER

Sponsor Role collaborator

The renmin hospital of wuhan university

UNKNOWN

Sponsor Role collaborator

Nanjing BenQ Hospital

UNKNOWN

Sponsor Role collaborator

China-Japan Friendship Hospital

OTHER

Sponsor Role collaborator

xinan hospital

UNKNOWN

Sponsor Role collaborator

Wu Hu Yijishan hospital

UNKNOWN

Sponsor Role collaborator

The fifth affiliated hospital of zhong shan university

UNKNOWN

Sponsor Role collaborator

Beijing Jishuitan Hospital

OTHER

Sponsor Role lead

Responsible Party

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xiaoguang Cheng

professor of radiology, chairman of department

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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xiaoguang cheng, MD

Role: PRINCIPAL_INVESTIGATOR

Beijing Jishuitan Hospital

qiang zeng

Role: PRINCIPAL_INVESTIGATOR

General PLA hospital

Locations

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Wu Hu Yijishan Hospital

Wuhu, Anhui, China

Site Status RECRUITING

Beijing Jishuitan hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

The first affiliated hospital of Guiyang Medical University

Guiyang, Guizhou, China

Site Status RECRUITING

The first affiliated hospital of Zhengzhou University

Zhengzhou, Henan, China

Site Status RECRUITING

Hua Shan hospital

Shanghai, Shanghai Municipality, China

Site Status RECRUITING

Shanghai Ruijin hospital

Shanghai, Shanghai Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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xiaoguang cheng, md

Role: CONTACT

0086-010-58516947

xiaoxia fu, md

Role: CONTACT

0086-13683132746

Facility Contacts

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xiaojun zha

Role: primary

008613705533568

Kai Li, PhD

Role: primary

008615801633664

Xia Du, MD

Role: primary

008613765071289

Yan Wu, MD

Role: primary

008613803843588

Shuang chen

Role: primary

008613601717952

Yong Lu, MD

Role: primary

008613701995934

References

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Sun Y, Qi X, Wang X, Lin X, Zhou Y, Du Y, Liu A, Lv X, Zhou J, Li Z, Wu X, Zou Z, Zhang M, Zhu J, Shang F, Li Y, Li H. Association between high-density lipoprotein cholesterol and lumbar bone mineral density in Chinese: a large cross-sectional study. Lipids Health Dis. 2024 Jan 24;23(1):27. doi: 10.1186/s12944-024-02023-1.

Reference Type DERIVED
PMID: 38267987 (View on PubMed)

Sun Y, Qi X, Lin X, Zhou Y, Lv X, Zhou J, Li Z, Wu X, Zou Z, Li Y, Li H. Association between total cholesterol and lumbar bone density in Chinese: a study of physical examination data from 2018 to 2023. Lipids Health Dis. 2023 Oct 21;22(1):180. doi: 10.1186/s12944-023-01946-5.

Reference Type DERIVED
PMID: 37865752 (View on PubMed)

Cheng X, Zhao K, Zha X, Du X, Li Y, Chen S, Wu Y, Li S, Lu Y, Zhang Y, Xiao X, Li Y, Ma X, Gong X, Chen W, Yang Y, Jiao J, Chen B, Lv Y, Gao J, Hong G, Pan Y, Yan Y, Qi H, Ran L, Zhai J, Wang L, Li K, Fu H, Wu J, Liu S, Blake GM, Pickhardt PJ, Ma Y, Fu X, Dong S, Zeng Q, Guo Z, Hind K, Engelke K, Tian W; China Health Big Data (China Biobank) project investigators. Opportunistic Screening Using Low-Dose CT and the Prevalence of Osteoporosis in China: A Nationwide, Multicenter Study. J Bone Miner Res. 2021 Mar;36(3):427-435. doi: 10.1002/jbmr.4187. Epub 2020 Nov 4.

Reference Type DERIVED
PMID: 33145809 (View on PubMed)

Other Identifiers

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jst2018

Identifier Type: -

Identifier Source: org_study_id

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