High Sensitive CRP in Prediabetics and Diabetes

NCT ID: NCT03673904

Last Updated: 2018-09-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

180 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-01-01

Study Completion Date

2018-03-08

Brief Summary

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The aim of this study was to study the level of high-sensitivity CRP in sera of pre-diabetic and newly diagnosed patients with type 2 diabetes mellitus and its correlation with HOMA IR and HbA1c

Detailed Description

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This study will include (180) subjects, 60 pre-diabetic patients, 60 patients with newly diagnosed type 2 diabetes ( within one month of diagnosis) and 60 normal healthy non diabetic individuals as a control group. The study individuals will be recruited from the Diabetes and Internal Medicine Clinics of Fayoum University Hospital

Conditions

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Assess Level of High Sensitive CRP in Diabetics and Prediabetics

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Prediabetics

Ages ranging from 18 to 60 years old,males and females were included . A fasting blood glucose level (100 to 125 mg/dL). or A 2-hour blood glucose level (140 to 199 mg/dL) .or Hb A1C 5.7% to 6.4%.

No interventions assigned to this group

Newly diagnosed type 2 diabetes

Ages ranging from 18 to 60 years old,males and females were included Newly diagnosed type 2 diabetes: (maximum within one month from diagnosis) A fasting blood glucose level \>126 mg/dl A 2-hour blood glucose level \> 200 mg/d Hb A1C \> 6.5%

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Pre-diabetic patients:

* A fasting blood glucose level (100 to 125 mg/dL). or
* A 2-hour blood glucose level (140 to 199 mg/dL) .or
* Hb A1C 5.7% to 6.4%.
* Newly diagnosed type 2 diabetes: (maximum within one month from diagnosis)

* A fasting blood glucose level \>126 mg/dl
* A 2-hour blood glucose level \> 200 mg/dl
* Hb A1C \> 6.5%

Exclusion Criteria

* Pregnant or lactating females.
* Patients who have recent infection.
* Patients with acute inflammatory diseases as autoimmune diseases.
* Patients with malignancy or on chemotherapy.
* Patients with acute or chronic liver or renal diseases
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fayoum University

OTHER

Sponsor Role lead

Responsible Party

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Ahmed Abdelkawi Hammad

Lecturer of internal medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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D84

Identifier Type: -

Identifier Source: org_study_id

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