High-sensitivity C-reactive Protein and United Kingdom Prospective Diabetes Study (UKPDS) Risk Score in Type 2 Diabetes

NCT ID: NCT01099865

Last Updated: 2010-04-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

56 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-12-31

Study Completion Date

2010-04-30

Brief Summary

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The UKPDS risk score is recommended to assess global risk for future coronary heart disease (CHD) events in primary prevention. Recently, high-sensitivity C-reactive protein (hsCRP) has emerged as a strong independent risk factor for CHD. 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is a promising imaging technique for the evaluation of vascular inflammation that reflects vulnerable atherosclerotic plaque.

Detailed Description

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Conditions

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Atherosclerosis Type 2 Diabetes

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

* Type 2 diabetes

Exclusion Criteria

* Myocardial infarction, unstable angina, stroke, peripheral artery disease, or cardiovascular revascularization
* Resting blood pressure ≥160/100 mmHg
* Malignancy, or severe renal or hepatic disease
* Participants were free of any lipid-lowering therapies and postmenopausal hormone replacement therapy at least the 6 month period prior to enrollment
* History of inflammatory condition or those taking medications that might affect inflammatory status within 6 months
Minimum Eligible Age

16 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Korea University

OTHER

Sponsor Role lead

Responsible Party

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IRB

Locations

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Korea University Guro Hospital Dept. of Endocrinology

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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PET(DM)

Identifier Type: -

Identifier Source: org_study_id

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