Correlation Between Micro Vascular Complications and Severity of Coronary Artery Disease in Type 2 DM

NCT ID: NCT04975828

Last Updated: 2022-02-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

70 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-06-01

Study Completion Date

2022-01-01

Brief Summary

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Diabetes is a major cause of morbidity and mortality worldwide and it contributes substantially to healthcare costs. Type 2 Diabetes mellitus is the most common type of diabetes accounting for approximately (90%) of all cases.

Type 2 DM carries a two to six times risk of death from cardiovascular etiologies, such that age adjusted prevalence of white Americans for coronary artery disease (CAD) is double in those with type 2 DM than those without .

Detailed Description

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Conditions

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Patients With Type 2 DM Who Underwent Coronary Angiography Due to Coronary Artery Disease and Presence of Microvascular Complications in Same Patients

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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patients type 2 DM with coronary artery disease and diabetic retinopathy.

albumin creatinine ratio -EGFR-fundus examination- coronary angiography.

Intervention Type DIAGNOSTIC_TEST

albumin creatinine ratio and EGFR to assess. diabetic nephropathy. fundus examination to assess. diabetic retinopathy. assess of coronary artery disease by coronary angiography. assess diabetic nephropathy by neurologic examination.

patients type 2 DM with coronary artery disease and diabetic neuropathy.

albumin creatinine ratio -EGFR-fundus examination- coronary angiography.

Intervention Type DIAGNOSTIC_TEST

albumin creatinine ratio and EGFR to assess. diabetic nephropathy. fundus examination to assess. diabetic retinopathy. assess of coronary artery disease by coronary angiography. assess diabetic nephropathy by neurologic examination.

patients type 2 DM with coronary artery disease and diabetic nephropathy

albumin creatinine ratio -EGFR-fundus examination- coronary angiography.

Intervention Type DIAGNOSTIC_TEST

albumin creatinine ratio and EGFR to assess. diabetic nephropathy. fundus examination to assess. diabetic retinopathy. assess of coronary artery disease by coronary angiography. assess diabetic nephropathy by neurologic examination.

patient type 2 DM with coronary artery disease and non microvascular complications.

albumin creatinine ratio -EGFR-fundus examination- coronary angiography.

Intervention Type DIAGNOSTIC_TEST

albumin creatinine ratio and EGFR to assess. diabetic nephropathy. fundus examination to assess. diabetic retinopathy. assess of coronary artery disease by coronary angiography. assess diabetic nephropathy by neurologic examination.

Interventions

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albumin creatinine ratio -EGFR-fundus examination- coronary angiography.

albumin creatinine ratio and EGFR to assess. diabetic nephropathy. fundus examination to assess. diabetic retinopathy. assess of coronary artery disease by coronary angiography. assess diabetic nephropathy by neurologic examination.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

100 Cases were selected with type II (DM) patients who had been admitted for coronary angiography because of suspected (CAD) to the Catheter lab unit of Sohag University Hospital.

Exclusion Criteria

1. Type 1 DM.
2. Smoker.
3. Hypertension.
4. Pregnant women.
5. Patient known non diabetic retinal disease non diabetic. nephropathy or neuropathy.
6. History of familial dyslipidemia.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sohag University

OTHER

Sponsor Role lead

Responsible Party

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Islam Khaled Fathy

resident at internal medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Osama R Elsherief

Sohag, , Egypt

Site Status

Countries

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Egypt

References

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Ybarra-Munoz J, Jurado-Campos J, Garcia-Gil M, Zabaleta-Del-Olmo E, Mir-Coll T, Zabalegui A, Vidal J, Romeo JH. Cardiovascular disease predicts diabetic peripheral polyneuropathy in subjects with type 2 diabetes: A 10-year prospective study. Eur J Cardiovasc Nurs. 2016 Jun;15(4):248-54. doi: 10.1177/1474515114565215. Epub 2014 Dec 19.

Reference Type BACKGROUND
PMID: 25527522 (View on PubMed)

Dal Canto E, Ceriello A, Ryden L, Ferrini M, Hansen TB, Schnell O, Standl E, Beulens JW. Diabetes as a cardiovascular risk factor: An overview of global trends of macro and micro vascular complications. Eur J Prev Cardiol. 2019 Dec;26(2_suppl):25-32. doi: 10.1177/2047487319878371. Epub 2019 Nov 13.

Reference Type BACKGROUND
PMID: 31722562 (View on PubMed)

Glovaci D, Fan W, Wong ND. Epidemiology of Diabetes Mellitus and Cardiovascular Disease. Curr Cardiol Rep. 2019 Mar 4;21(4):21. doi: 10.1007/s11886-019-1107-y.

Reference Type BACKGROUND
PMID: 30828746 (View on PubMed)

Other Identifiers

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Soh-Med-21-07-02

Identifier Type: -

Identifier Source: org_study_id

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