C-reactive Protein and Endothelial Dysfunction in Women With Glucose Intolerance

NCT ID: NCT00589355

Last Updated: 2020-04-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

46 participants

Study Classification

OBSERVATIONAL

Study Start Date

2002-01-31

Study Completion Date

2008-10-01

Brief Summary

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The goal of this study is to determine whether markers of vascular inflammation (such as c-reactive protein) can predict endothelial dysfunction (as measured by flow-mediated dilation) in postmenopausal women with glucose intolerance compared to normal controls.

Detailed Description

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Conditions

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Glucose Intolerance

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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1

postmenopausal women with glucose intolerance (either pre-diabetes or diet-controlled diabetes)

No interventions assigned to this group

2

postmenopausal women with normal glucose tolerance

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* healthy postmenopausal women
* ages 40-65

Exclusion Criteria

* smokers
* diabetes requiring medication
Minimum Eligible Age

40 Years

Maximum Eligible Age

65 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Yale University

OTHER

Sponsor Role lead

Responsible Party

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Yale University School of Medicine

Principal Investigators

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Barbara I Gulanski, MD, MPH

Role: PRINCIPAL_INVESTIGATOR

Yale University

Locations

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Yale Center for Clinical Investigation

New Haven, Connecticut, United States

Site Status

Countries

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United States

Other Identifiers

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12110

Identifier Type: -

Identifier Source: org_study_id

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