The Biological Rhythm of Human Metabolite

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-05-01

Study Completion Date

2050-05-01

Brief Summary

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The circadian regulation in mammals have been known for a long time. A special group of clock genes, organized in feedback loops, are responsible for the circadian regulation in both the SCN and peripheral organs. The central clock is mainly entrained by the light-dark cycle, while the peripheral ones in organs such as liver and intestine, are more influenced by the feeding-fasting cycles. The coordination of central and peripheral clocks is thought to be essential in the maintenance of physiological homeostasis.This study aim to investigate the association between biological rhythm and metabolism.

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Detailed Description

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Conditions

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Rhythm Nodal Metabolism and Nutrition Disorder Metabolism Disorder, Lipid

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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male, non-obese

male with BMI\<28

No interventions assigned to this group

male, obese

male with BMI≥28

No interventions assigned to this group

female, non-obese

female with BMI\<28

No interventions assigned to this group

female, obese

female with BMI≥28

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Male or female；
* Aged of 18 to 30 years old;

Exclusion Criteria

* Presence of pituitary/hypothalamic disorders, polycystic ovarian syndrome， thyroid disorders, hypertension, malignant tumor, cardiac insufficiency，hepatic or renal insufficiency, gastrointestinal disorders and acute infection;
* Receiving psychotropic or hormonal medications including hormonal contraception and hormone therapies;
* Taking lipid-lowering agents or hypoglycemic agents and other drugs that known to influence cardiovascular health;
* Pregnancy or lactation women;
* Obviously poor compliance.

Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes