Evaluation of The Effect of Live Probiotic Cultures Present in Fermented Dairy Product (Yogurt) Versus The Effect of Freeze-Dried Probiotic Sachets on Gingival Bleeding of Adolescents

NCT ID: NCT03640065

Last Updated: 2020-12-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-10-20

Study Completion Date

2020-03-31

Brief Summary

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To evaluate the effect of probiotics supplied in two different forms (dairy products containing probiotics as yogurt and freeze-dried synthetic probiotics sachets) on improving gingival condition and caries potentiality of dental plaque in adolescents

Detailed Description

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Conditions

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Gingival Inflammation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

only statistician was blind known participants only by codes

Study Groups

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freeze-dried probiotic sachets

Group Type EXPERIMENTAL

freeze-dried probiotic sachets

Intervention Type DRUG

* The participants will be instructed to consume the sachets as follow, each sachet powder is mixed with 10 ml of water in a measuring cup, then swish the mixture in the mouth for one minute before swallowing.
* This procedure will be repeated once daily for the following 4 weeks.
* 4 weeks supply will be given to the participants.

fermented dairy product (yogurt)

Group Type ACTIVE_COMPARATOR

fermented dairy product ( yogurt)

Intervention Type DIETARY_SUPPLEMENT

* The participants will be instructed to consume the yogurt once daily regularly for the following 4 weeks.
* 4 weeks supply will be given to the participants with instruction to store the yogurt in refrigerator at home

Interventions

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freeze-dried probiotic sachets

* The participants will be instructed to consume the sachets as follow, each sachet powder is mixed with 10 ml of water in a measuring cup, then swish the mixture in the mouth for one minute before swallowing.
* This procedure will be repeated once daily for the following 4 weeks.
* 4 weeks supply will be given to the participants.

Intervention Type DRUG

fermented dairy product ( yogurt)

* The participants will be instructed to consume the yogurt once daily regularly for the following 4 weeks.
* 4 weeks supply will be given to the participants with instruction to store the yogurt in refrigerator at home

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

1. Children aged 12-15 years old
2. Children complaining from gingival problems
3. Medically free children
4. Children not registered in other clinical researches

Exclusion Criteria

1. Children with systemic diseases, mental disorders, chronic debilitating diseases.
2. Children using antibiotic treatment during the study
3. Children with orthodontic treatment
4. Children using antimicrobial mouthwash
5. Children taking any probiotic supplemental therapy
Minimum Eligible Age

12 Years

Maximum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Mai Mustafa Samy Ismaiel

principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Mai M Ismaiel

Cairo, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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CEBD-CU-2018-06-40

Identifier Type: -

Identifier Source: org_study_id