Microbiological Epidemiology in Patients Experiencing Microbiological or Clinical Failure Following Reimplantation After a 2-stage Exchange Strategy for Hip or Knee Prosthetic Joint Infection

NCT ID: NCT03627000

Last Updated: 2018-08-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

114 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-10-01

Study Completion Date

2018-04-01

Brief Summary

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This study concerns patients having had an infection on their prosthesis (hip, knee,..) and for whom a 2-step exchange of prosthesis has been done.

A 2-step exchange consists in explantation of the prosthesis and implementation of a spacer at the first stage, and reimplantation of a new prosthesis in a second stage. Patients with late prosthetic joint infection are at risk for superinfection at the time of reimplantation.

The aim is to determine the microbiological epidemiology in patients experiencing failure following reimplantation to establish, based on the drug susceptibilities, which cement could be the most active.

Detailed Description

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Conditions

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Bone and Joint Infection Bacterial Infections EPIDEMIOLOGY

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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failure after reimplantation

description of the failure at the reimplantation

failure after reimplantation

Intervention Type OTHER

description of cinical and microbiological failure

Interventions

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failure after reimplantation

description of cinical and microbiological failure

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* patients with prosthetic joint infection having had a 2-step exchange at least from the reimplantation, between 2013 and 2015.

Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hospices Civils de Lyon

OTHER

Sponsor Role lead

Responsible Party

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Eugénie MABRUT

Clinical Research Assistant

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Tristan FERRY, Md,PhD

Role: PRINCIPAL_INVESTIGATOR

Hospices Civils de Lyon Hôpital de la Croix-Rousse

Other Identifiers

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17-089-2

Identifier Type: -

Identifier Source: org_study_id

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