Home
Clinical Trials
Retrospective Review of Cache...

Retrospective Review of Cachexia in Lung and Gastrointestinal Cancer Patients

Last Updated: 2025-04-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

20000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-11-26

Study Completion Date

2027-03-18

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The objective is to perform a retrospective chart review of patients with cachexia related to cancer in patients treated at UT Southwestern Medical Center and Parkland Hospital to evaluate the prognosis and practice patterns in management of cachexia and associated symptoms.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Cancer-associated Cachexia in Patients With Incurable Gastroesophageal Cancer

NCT06137508

Gastro-Esophageal Cancer

RECRUITING

Prevalence of Cachexia in Patients Undergoing Chemotherapy

NCT01939340

Cancer Cachexia

COMPLETED

Skeletal Muscle Energy Metabolism in Undernourished Patients With Gastrointestinal Cancer

NCT02573974

Undernutrition Gastrointestinal Cancer

COMPLETED NA

Prevalence of Enteral Nutrition Interruption in an Oncology Intensive Care Unit.

NCT06156189

Critical Illness

COMPLETED

Sarcopenia and Visceral Obesity in Esophageal and Gastric Cancer

NCT03061370

Esophageal Cancer Gastric Cancer Sarcopenia +9 more

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The definition of cachexia has not been fully elucidated, but there are many similar parameters and guidelines associated with identifying patients with cachexia. Cachexia is a clinical diagnosis associated with weight loss, decreased muscle mass (sarcopenia), decreased strength, fatigue, and an increased inflammatory state. Patients with cachexia have a poorer prognosis than patients who have maintained their weight. Also, patients who have lost weight prior to initiating definitive therapy have worse side effects from subsequent therapy.

This study involves no treatment or invasive procedures. The chart review will attempt to characterize lung and gastrointestinal cancer related cachexia in the setting of a palliative care clinic including both primary treatment and treatment at the time of recurrence. Interventions in cachectic patients for weight control including nutritional support and supplements, pain control, anti-inflammatory medications, and appetite stimulants will be tracked along with clinical markers including weight and laboratory values.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cachexia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

Medical charts representing patients with a diagnosis of lung or gastrointestinal cancer with a tissue diagnosis from 1/1/2005 and onward treated at UT Southwestern or Parkland.

Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers