Effects of Low Intensity, High Intensity Eccentric Resistance Training Associated With Blood Flow Restriction

NCT ID: NCT03601104

Last Updated: 2021-03-09

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 61 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2019-03-12
• Study Completion Date: 2020-12-31

Brief Summary

Introduction: studies on resistance training of low intensity associated with blood flow restriction in recent years, although there are still gaps that can be explored in relation to their physiological phenomena when associated with eccentric training. In this way, from there the exploration becomes relevant the investigation of eccentric training associated to an RFS. Objective: To analyze and compare the effects of a high intensity and low intensity intensive resistance training associated with an RFS (TREAI-RFS and TREBI-RFS) with a high intensity eccentric resistance training without RFS (TREAI) in knee extensors. Method: The study will consist of 45 male participants, allocated from a stratified randomization into three groups: TREAI (n = 15), TREAI-RFS (n = 15) and TREBI-RFS (n = 15). Participants underwent a training program with a minimum of 40% without RFS, 80% with RFS and 40% with CVS of CVIM, 3 times a week, and the outcomes of muscle strength, muscle structure, power test and Endothelial growth will be assessed one week before, the fourth week and one week after the end of the training program. In addition, clinical markers of perception and recovery effort are investigated before and after a session. The graph used is descriptive and descriptive, as it is used as a model of analysis of variance for the analysis of replications without a two-factor scheme, which provides detailed information on how the measures are repeated, neither. A whole statistical analysis can reach the level of significance of 5%.

Conditions

Exercise

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: OTHER
• Blinding Strategy: SINGLE

Study Groups

HIET (n = 15)

High intensity eccentric training: A high intensity (80% isometric peak) eccentric training of the knee extensors in the isokinetic will be performed during 6 weeks, 3 times a week.

Group Type: ACTIVE_COMPARATOR

High intensity eccentric training

Intervention Type: OTHER

High intensity eccentric training group with 80% of isometric peak torque.

HIET-BFR (n= 15)

High intensity eccentric training with blood flow restriction (BFR): A high intensity eccentric (80% isometric peak) training of the knee extensors in isokinetic will be performed, associated with a pressure cuff placed in the proximal thigh (40% of absolute occlusion pressure) for 6 weeks, 3 times a week.

Group Type: EXPERIMENTAL

High intensity eccentric training with BFR

Intervention Type: OTHER

Eccentric high intensity training group with 80% of isometric peak torque associated with blood flow restriction (40% of absolute occlusion pressure).

LIET-BFR (n = 15)

Low intensity eccentric training with blood flow restriction (BFR): A low intensity eccentric (40% isometric peak) training of the knee extensors in isokinetic will be performed associated with a pressure cuff placed in the proximal thigh (40% absolute occlusion pressure) for 6 weeks, 3 times a week.

Group Type: EXPERIMENTAL

Low intensity eccentric training with BFR

Intervention Type: OTHER

Low intensity eccentric training group with 40% of isometric peak torque associated with blood flow restriction (40% of absolute occlusion pressure).

LIET (n= 15)

Low intensity eccentric training: A low intensity (40% isometric peak) eccentric training of the knee extensors in the isokinetic will be performed during 6 weeks, 3 times a week.

Group Type: ACTIVE_COMPARATOR

Low intensity eccentric training

Intervention Type: OTHER

Low intensity eccentric training group with 40% of isometric peak torque

Interventions

High intensity eccentric training

High intensity eccentric training group with 80% of isometric peak torque.

Intervention Type: OTHER

High intensity eccentric training with BFR

Eccentric high intensity training group with 80% of isometric peak torque associated with blood flow restriction (40% of absolute occlusion pressure).

Intervention Type: OTHER

Low intensity eccentric training with BFR

Low intensity eccentric training group with 40% of isometric peak torque associated with blood flow restriction (40% of absolute occlusion pressure).

Intervention Type: OTHER

Low intensity eccentric training

Low intensity eccentric training group with 40% of isometric peak torque

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• male sex;
• healthy;
• aged between 18 and 35 years

Exclusion Criteria

• smokers;
• alcoholics;
• use drugs that influenced cardiac autonomic activity;
• cardiovascular, metabolic or endocrine diseases.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 35 Years
• Eligible Sex: MALE
• Accepts Healthy Volunteers: Yes

Sponsors

Paulista University

OTHER

Sponsor Role: lead

Responsible Party

Franciele Marques Vanderle

PhD

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Franciele Marques Vanderlei, PhD

Role: PRINCIPAL_INVESTIGATOR

Universidade Estadual Paulista - FCT / UNESP

Locations

Franciele Marques Vanderlei

Presidente Prudente, São Paulo, Brazil

Countries

Brazil

Other Identifiers

680075683140

Identifier Type: -

Identifier Source: org_study_id