Neurodynamic Interventions for Multiple Sclerosis

NCT ID: NCT03595631

Last Updated: 2018-10-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

32 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-07-26

Study Completion Date

2018-10-04

Brief Summary

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A randomized, parallel-group, clinical trial will be conducted to compare the immediate effects of the inclusion of a neurodynamic intervention into a multimodal physiotherapy program on pressure pain sensitivity, pain and manual dexterity in patients with multiple sclerosis

Detailed Description

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Conditions

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Multiple Sclerosis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Physical Therapy

Patients will receive 5 session of multimodal physiotherapy treatment of 30min duration including low-load strength exercises, soft tissue mobilization and muscle-tendon stretching exercises twice per week.

Group Type ACTIVE_COMPARATOR

Physical Therapy

Intervention Type OTHER

Patients will receive 5 session of multimodal physiotherapy treatment of 30min duration including low-load strength exercises, soft tissue mobilization and muscle-tendon stretching exercises twice per week.

Physical Therapy plus neurodynamic

Patients will receive 5 session of multimodal physiotherapy treatment of 30min duration including low-load strength exercises, soft tissue mobilization and muscle-tendon stretching exercises twice per week. In addition, they will also receive bilateral nerve slider neurodynamic interventions targeting the median, ulnar and radial nerves.

Group Type EXPERIMENTAL

Physical Therapy plus Neurodynamic

Intervention Type OTHER

Patients will receive 5 session of multimodal physiotherapy treatment of 30min duration including low-load strength exercises, soft tissue mobilization and muscle-tendon stretching exercises twice per week. In addition, they will also receive bilateral nerve slider neurodynamic interventions targeting the median, ulnar and radial nerves.

Interventions

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Physical Therapy

Patients will receive 5 session of multimodal physiotherapy treatment of 30min duration including low-load strength exercises, soft tissue mobilization and muscle-tendon stretching exercises twice per week.

Intervention Type OTHER

Physical Therapy plus Neurodynamic

Patients will receive 5 session of multimodal physiotherapy treatment of 30min duration including low-load strength exercises, soft tissue mobilization and muscle-tendon stretching exercises twice per week. In addition, they will also receive bilateral nerve slider neurodynamic interventions targeting the median, ulnar and radial nerves.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* a diagnosis of multiple sclerosis according to the modified McDonald criteria;
* symptoms of paresthesia and lack of sensitivity in the upper extremity;
* Expanded Disability Status Scale (EDSS) between 0 and 6.5 points;
* absence of cognitive deficit.

Exclusion Criteria

* any exacerbation of multiple sclerosis during the previous 3 months;
* previous hand surgery or steroid injections treatment in the upper extremity;
* multiple diagnoses on the upper extremity (e.g., cervical radiculopathy);
* cervical, shoulder, or upper extremity trauma;
* other comorbid musculoskeletal medical conditions;
* mini-mental state examination \<25
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universidad Rey Juan Carlos

OTHER

Sponsor Role lead

Responsible Party

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César Fernández-de-las-Peñas

Director of Department

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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César Fernández-de-las-Peñas

Alcorcón, Madrid, Spain

Site Status

Countries

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Spain

References

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de Dios Perez-Bruzon J, Fernandez-de-Las-Penas C, Cleland JA, Plaza-Manzano G, Ortega-Santiago R. Effects of neurodynamic interventions on pain sensitivity and function in patients with multiple sclerosis: a randomized clinical trial. Physiotherapy. 2022 Jun;115:36-45. doi: 10.1016/j.physio.2021.04.004. Epub 2021 Apr 22.

Reference Type DERIVED
PMID: 35101724 (View on PubMed)

Other Identifiers

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PI-URJC 572

Identifier Type: -

Identifier Source: org_study_id

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