Pain Inhibitory Effects of Other Pain Induced by Mechanical Pressure at Different Intensities

NCT ID: NCT05730166

Last Updated: 2023-05-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-02-15

Study Completion Date

2023-04-21

Brief Summary

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The objective is to estimate the effects on pain thresholds of a painful mechanical stimulus on the upper trapezius at moderate intensity compared to mild intensity or non-painful.

Detailed Description

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The mechanical stimulus produced in manual therapy (MT) techniques elicits neurophysiological responses within the peripheral and central nervous system responsible for pain inhibition. Almost all types of MT elicit a neurophysiological response that is associated with the descending pain modulation circuit. But it has not been demonstrated whether this inhibition occurs through a conditioned pain modulation mechanism induced by painful mechanical stimulation that is carried out with manual therapy techniques.

Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Mechanical stimulation at moderate pain intensity

Mechanical compression is applied with the thumb to the upper trapezius muscle on the non-dominant side at the midpoint between the acromion and C7. The intensity of this will be regulated by the pain it causes the patient, trying to ensure that it is at all times approximately 5/10 on the numerical pain rating scale (NPRS) with 0 being "no pain at all" and 10 being "the worst pain imaginable". The stimulation will be carried out for 2 minutes.

Group Type EXPERIMENTAL

Mechanical Conditioning stimulus

Intervention Type OTHER

Mechanical stimulus on the upper trapezius of the non-dominant side.

Mechanical stimulation at mild pain intensity

Mechanical compression is applied with the thumb to the upper trapezius muscle on the non-dominant side at the midpoint between the acromion and C7. The intensity of this will be regulated by the pain it causes the patient, trying to ensure that it is at all times approximately 2/10 on the numerical pain rating scale (NPRS) with 0 being "no pain at all" and 10 being "the worst pain imaginable". The stimulation will be carried out for 2 minutes.

Group Type ACTIVE_COMPARATOR

Mechanical Conditioning stimulus

Intervention Type OTHER

Mechanical stimulus on the upper trapezius of the non-dominant side.

Painless mechanical stimulation

Mechanical compression is applied with the thumb to the upper trapezius muscle on the non-dominant side at the midpoint between the acromion and C7. The intensity of this will be regulated by the pain it causes the patient, trying to ensure that it is at all times approximately 0/10 on the numerical pain rating scale (NPRS) with 0 being "no pain at all" and 10 being "the worst pain imaginable". The stimulation will be carried out for 2 minutes.

Group Type ACTIVE_COMPARATOR

Mechanical Conditioning stimulus

Intervention Type OTHER

Mechanical stimulus on the upper trapezius of the non-dominant side.

Interventions

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Mechanical Conditioning stimulus

Mechanical stimulus on the upper trapezius of the non-dominant side.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* healthy male or female between 18 and 65 years
* Free of pain and with no history of chronic pain

Exclusion Criteria

* Pregnant or having given birth within the last year
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Josue Fernandez Carnero

OTHER

Sponsor Role lead

Responsible Party

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Josue Fernandez Carnero

Professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Josué Fernández Carnero, PhD

Role: PRINCIPAL_INVESTIGATOR

Universidad Rey Juan Carlos

Locations

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Universidad Rey Juan Carlos

Alcorcón, Madrid, Spain

Site Status

Countries

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Spain

Other Identifiers

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MechCPM2

Identifier Type: -

Identifier Source: org_study_id

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