CODP Imaging From a Dose Perspective

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1957 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-08-31

Study Completion Date

2017-09-30

Brief Summary

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The noncontrast-enhanced chest computed tomography (CT) is an emerging diagnostical tool in patient with chronic obstructive pulmonary disease (COPD). As shown in previous studies and pointed out by the Fleischner society, an additional scan in expiration reflects the pathophysiology of this complex disease better and extends the clinical information of the CT.

Nevertheless, this scan is leading to an increase in radiation dose. But currently it is unclear if this increased radiation dose is proportional to the additional clinical value when compared to inspiration-only protocols. Therefore, the aim of this study was to compare the organ specific radiation doses of a combined inspiration-expiration CT on a 3rd generation dual-source scanner with noncontrast-enhanced chest CTs of two clinical routine scanners. Therefore, the radiation doses of nearly 2000 chest CTs have been evaluated.

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Detailed Description

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Conditions

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Radiation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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16-slice CT scanner

1426 patients that have received a noncontrast-enhanced chest CT on our 16-slice clinical routine CT scanner in inspiration only.

computed tomography

Intervention Type DIAGNOSTIC_TEST

noncontrast-enhanced chest computed tomography

2nd generation dual-source CT

320 patients that have received a noncontrast-enhanced chest CT on our second generation dual-source CT scanner in inspiration only.

computed tomography

Intervention Type DIAGNOSTIC_TEST

noncontrast-enhanced chest computed tomography

3rd generation dual-source CT

211 patients that have received a noncontrast-enhanced chest CT on our third generation dual-source CT scanner in inspiration and expiration.

computed tomography

Intervention Type DIAGNOSTIC_TEST

noncontrast-enhanced chest computed tomography

Interventions

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computed tomography

noncontrast-enhanced chest computed tomography

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* noncontrast-enhanced chest CT performed on one of the named devices
* imaging performed between August 2014 and September 2017
* CT protocol used as previously specified