Examining Effects of Aerobic Exercise on Pain Sensation

NCT ID: NCT03546153

Last Updated: 2019-09-27

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 10 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2018-06-01
• Study Completion Date: 2019-09-01

Brief Summary

By doing this study, researchers hope to learn effects of aerobic exercise on over activated nervous system in people with chronic low back pain.

Detailed Description

Chronic low back pain is a common condition in the world. About 85% of people with low back pain do not know the cause of their pain. This leads to ineffective treatments.

Recently, the idea of an over activated nervous system is thought to be one of the main reasons for chronic pain. Over activated nervous system means pain processing areas in the spine or brain might be more sensitive. Aerobic exercise, such as walking and cycling, is often used to decrease chronic pain. Aerobic exercise is a form of physical exercise that strengthen the heart and lungs in order to improve the body's utilization of oxygen.

The researchers want to examine if aerobic exercise is effective in decreasing over activation of the nervous system. Gaining a better understanding of effects of aerobic exercise on the nervous system may lead to more effective treatments for low back pain.

Conditions

Chronic Low Back Pain

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Aerobic exercise program

Participants will complete 12 week exercise program.

Group Type: EXPERIMENTAL

Aerobic exercise program

Intervention Type: BEHAVIORAL

Exercise program consists of training for 60 minutes, three times per week for 12 weeks. Participants will use a treadmill, Nu stepper/bike or elliptical to exercise.

Interventions

Aerobic exercise program

Exercise program consists of training for 60 minutes, three times per week for 12 weeks. Participants will use a treadmill, Nu stepper/bike or elliptical to exercise.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Lower back pain (LBP) for more than 3 months
• A minimal pain level of 3 on the 0-10 pain numerical rating scale (NRS) in the last 7 days
• Can read and understand English.

Exclusion Criteria

• Nerve root compression that resulted in numbness or decrease in sensation in the areas for the pain sensitivity tests as reported by the subject
• cervical or thoracic pain as a main complaint
• spinal pathologies such as fracture, tumor, infection, and severe inflammation
• severe spinal deformity
• severe cardiovascular and neurological diseases
• cancer
• history of spinal surgery
• currently seeking active treatments for LBP other than medications
• resting blood pressure more than 160/90 mmHg 49
• currently taking blood thinning medications
• uncontrolled diabetes
• cannot have blood pressure taken
• participated in a similar trial in the past

• Minimum Eligible Age: 21 Years
• Maximum Eligible Age: 70 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University of Kansas Medical Center

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Neena Sharma, PT, PhD, CMPT

Role: PRINCIPAL_INVESTIGATOR

University of Kansas Medical Center

Locations

University of Kansas Medical Center

Kansas City, Kansas, United States

Countries

United States

Other Identifiers

STUDY00141062

Identifier Type: -

Identifier Source: org_study_id