Physiologic Effects of CPAP After Vascular Surgery

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

18 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-05-25

Study Completion Date

2019-07-01

Brief Summary

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This study aims to investigate, with a case-crossover design, the effects of a short course of preventive CPAP administered in the immediate postoperative period in patients at high-risk of developing postoperative pulmonary complications undergoing major vascular surgery.

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Detailed Description

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Conditions

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Postoperative Complications Respiratory Failure

Study Design

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Observational Model Type

CASE_CROSSOVER

Study Time Perspective

PROSPECTIVE

Study Groups

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Major open vascular surgery

Surgical procedures on the abdominal aorta requiring median abdominal incision

Postoperative preventive CPAP

Intervention Type DEVICE

Administration of a course of 2 hours of CPAP with 7.5 cmH2O pressure and 0.30 FIO2

Endovascular aortic repair

Abdominal aortic repair with endovascular approach

Postoperative preventive CPAP

Intervention Type DEVICE

Administration of a course of 2 hours of CPAP with 7.5 cmH2O pressure and 0.30 FIO2

Interventions

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Postoperative preventive CPAP

Administration of a course of 2 hours of CPAP with 7.5 cmH2O pressure and 0.30 FIO2

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Open or endovascular surgery on the abdominal aorta
* Surgical procedure requiring general anaesthesia and invasive intraoperative mechanical ventilation
* Intermediate-high risk of postoperative pulmonary complications (ARISCAT score ≥ 26)

Exclusion Criteria

* Prolonged post-operative invasive ventilation
* Invasive or non-invasive ventilation or oxygen therapy in the last month
* ASA class IV or V
* Emergency procedures
* Pneumothorax or active pulmonary infection
* Any contraindication to CPAP
* Prolonged bed rest
* Patient refusal to participate or to receive preventive CPAP

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No