Adhear Bone Conduction System

NCT ID: NCT03533686

Last Updated: 2023-08-08

Study Results

Results available

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Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

66 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-04-26

Study Completion Date

2022-03-18

Brief Summary

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The purpose of this research study is to learn about the hearing outcomes of adult and pediatric patients who are treated with or are candidates for bone conductive devices (also termed "BAHA"). Hearing outcomes will also be assessed with a second audio processor device called the Adhear System.

Detailed Description

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Conditions

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Hearing Loss, Conductive Hearing Loss, Unilateral

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Participants who are enrolled in Aims 3 are part of a cross-over design. Participants in this group will be randomly assigned to either standard of care followed by Adhear, or Adhear followed by standard of care.
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Single-Sided Deafness Adult (Aim1) Group

Adult participants with single-sided deafness and are experienced bone conduction device users (6 months minimum of bone conduction device use and no intermittent use within the last 2 weeks) with an abutment implant will be provided with the Adhear system for 2 weeks (plus up to 90 days).

Group Type EXPERIMENTAL

Adhear Bone Conduction System

Intervention Type DEVICE

Non-invasive bone conduction hearing device using adhesive

Conductive Hearing Loss Adult (Aim 2) Group

Adult participants with conductive hearing loss and are experienced bone conduction device users (6 months minimum of bone conduction device use and no intermittent use within the last 2 weeks) with an abutment implant will be provided with the Adhear system for 2 weeks (plus up to 90 days).

Group Type EXPERIMENTAL

Adhear Bone Conduction System

Intervention Type DEVICE

Non-invasive bone conduction hearing device using adhesive

Adhear followed by BAHA (Aim 3) Group

Pediatric participants (aged 5-17 years) and their parents with conductive hearing loss or single-sided deafness who have not previously used a bone conduction device, will be provided with the Adhear system for 3 weeks (plus up to 90 days) followed by bone anchored hearing aid (BAHA) for another 3 weeks (plus up to 90 days).

Group Type EXPERIMENTAL

Adhear Bone Conduction System

Intervention Type DEVICE

Non-invasive bone conduction hearing device using adhesive

Bone anchored hearing aid (BAHA)

Intervention Type DEVICE

Non-invasive bone conduction hearing device using a headband

BAHA followed by Adhear (Aim 3) Group

Pediatric participants (aged 5-17 years) and their parents with conductive hearing loss or single-sided deafness who have not previously used a bone conduction device, will be provided with the BAHA system for 3 weeks (plus up to 90 days) followed by Adhear for another 3 weeks (plus up to 90 days).

Group Type EXPERIMENTAL

Adhear Bone Conduction System

Intervention Type DEVICE

Non-invasive bone conduction hearing device using adhesive

Bone anchored hearing aid (BAHA)

Intervention Type DEVICE

Non-invasive bone conduction hearing device using a headband

Pediatric Unilateral Conductive Hearing Loss (Aim 3a) Group

Pediatric participants (aged 2-17 years) and their parents with unilateral conductive hearing loss and are experienced bone conduction device users (6 months minimum of bone conduction device use) on a headband will be provided with the Adhear system for 2 weeks (plus up to 90 days).

Group Type EXPERIMENTAL

Adhear Bone Conduction System

Intervention Type DEVICE

Non-invasive bone conduction hearing device using adhesive

Pediatric Bilateral Conductive Hearing Loss (Aim 3b) Group

Pediatric participants (aged 2-17 years) and their parents with bilateral conductive hearing loss and are experienced bone conduction device users (6 months minimum of bone conduction device use) on a headband will be provided with the Adhear system. Participants who are fitted bilaterally will receive 2 Adhear systems (one for each ear) for 2 weeks (plus up to 90 days) at Visit 1. Participants who are fitted unilaterally will receive 1 Adhear system for 2 weeks (plus up to 90 days) at Visit 1, afterwards, will be fitted bilaterally at Visit 2 and receive the Adhear system for both ears for another 2 weeks (plus up to 90 days) for a total of 4 weeks (plus up to 180 days).

Group Type EXPERIMENTAL

Adhear Bone Conduction System

Intervention Type DEVICE

Non-invasive bone conduction hearing device using adhesive

Interventions

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Adhear Bone Conduction System

Non-invasive bone conduction hearing device using adhesive

Intervention Type DEVICE

Bone anchored hearing aid (BAHA)

Non-invasive bone conduction hearing device using a headband

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

Aims 1 and 2:

* Adult English speaking patients who are experienced users of Bone Anchored Implants (BAIs) for the indication of either single sided deafness or conductive hearing loss.
* Experienced will be defined as greater than 6 months of device use and no intermittent function of the device within 2 weeks of enrollment.
* Subjects will be limited to those who have normal hearing by bone conduction defined as a pure tone average of 25 dBHL or better at 500, 1000, 2000, \& 3000 Hz in at least one ear.

Aim 3:

* English speaking children 5 to 17 years of age and their primary guardian who present to the clinic for treatment by BAI on a headband device for the indications of single sided deafness or conductive hearing loss.
* Subjects will be limited to those who have no prior use of a BAI or bone conduction hearing device, normal hearing by bone conduction defined as a pure tone average of 25 dBHL or better at 500, 1000, 2000, \& 3000 Hz in at least one ear. For those children where this cannot be definitively established, children will be included who display clinical signs of normal bone conduction hearing beyond a reasonable doubt and may include such evidence as (but not limited to): auditory brainstem response, speech awareness thresholds, visual reinforcement audiometry, conditioning play audiometry, CT scans, etc.)

Aim 3 a \& b:

* Pediatric bilateral or unilateral conductive hearing loss patients who are between the ages of 2 and 17 years of age
* Pediatric participants who are currently managed by the University of Miami with a bone conduction device attached to a softband.

Exclusion Criteria

Aims 1 \& 2:

* Non-English speakers
* Participants reporting allergies to adhesives or highly reactive skin.

Aim 3:

* Pediatric participants who are non-English speakers.
* Children who have previous experience with a BAI or bone conduction hearing device will not be included for study.
* Pediatric participants reporting allergies to adhesives or highly reactive skin.

Aims 3a \& 3b:

* Pediatric participants who are non-English speakers.
* Pediatric participants reporting allergies to adhesives or highly reactive skin.
Minimum Eligible Age

2 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Med-El Corporation

INDUSTRY

Sponsor Role collaborator

University of Miami

OTHER

Sponsor Role lead

Responsible Party

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Hillary A Snapp

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hillary Snapp, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Miami

Locations

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University of Miami Department of Otolaryngology

Miami, Florida, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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20161220

Identifier Type: -

Identifier Source: org_study_id

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