Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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WITHDRAWN
OBSERVATIONAL
2018-05-21
2021-09-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
CROSS_SECTIONAL
Study Groups
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CVD subjects
CVD will be defined as \>50% stenosis of one or more coronary arteries as assessed by coronary angiography.
isolation of endothelial cells precursors in blood
Circulating endothelial precursor cells will be isolated and then cultured in vitro. RNA will be then isolated.
healthy controls
healthy controls defined as not having stenosis of coronary arteries as assessed by coronary angiography.
isolation of endothelial cells precursors in blood
Circulating endothelial precursor cells will be isolated and then cultured in vitro. RNA will be then isolated.
Interventions
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isolation of endothelial cells precursors in blood
Circulating endothelial precursor cells will be isolated and then cultured in vitro. RNA will be then isolated.
Eligibility Criteria
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Inclusion Criteria
• absence of coronary artery stenosis
Exclusion Criteria
* chronic kidney disease,
* other chronic diseases
* dyslipidemia (fasting plasma LDL-C \>160 mg/dL and triglyceride levels \>150 mg/dL)
30 Years
60 Years
ALL
Yes
Sponsors
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Massachusetts General Hospital
OTHER
Tufts University
OTHER
Responsible Party
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Stefania lamon-Fava
Scientist I, Associate Professor
Principal Investigators
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Stefania Lamon-Fava, PhD
Role: PRINCIPAL_INVESTIGATOR
Tufts University
Locations
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Tufts Medical Center - Cardiovascular Clinic
Boston, Massachusetts, United States
Countries
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Other Identifiers
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12841
Identifier Type: -
Identifier Source: org_study_id
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