Chemotherapy Efficacy and Follow-up Study of Hepatitis B Virus Infection and Reactivation in Children With Leukemia

NCT ID: NCT03529760

Last Updated: 2019-07-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

600 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-05-08

Study Completion Date

2020-05-30

Brief Summary

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Children with clinically diagnosed leukemia may experience occult HBV infection after chemotherapy immunosuppressive therapy, which may affect the normal course of leukemia treatment. However, this is not caused by clinically relevant diagnosis and treatment measures but exists in vivo.

Detailed Description

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The clinical diagnosis of children with leukemia may be due to the influence of leukemia disease on the immune cells of the children and the damage to the immune system due to immunosuppressive therapy in children. Therefore, the risk of contracting hepatitis B virus is relatively high, and some children are In the treatment of immunosuppressive chemotherapy (later), the reactivation of occult HBV infection has an impact on the normal course of leukemia treatment. However, this is not a clinically relevant diagnosis and treatment measure. It is necessary to avoid unnecessary conflicts between clinical doctors and patients as much as possible.

Conditions

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Reactivation of Hepatitis B Virus

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

The clinical diagnosis of children with leukemia received systemic chemotherapy.

Exclusion Criteria

Children with non-leukemia and children without appropriate treatment.
Minimum Eligible Age

1 Year

Maximum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Children's Hospital of Chongqing Medical University

OTHER

Sponsor Role lead

Responsible Party

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Qiu Li

Director

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Yao Zhao

Role: STUDY_DIRECTOR

Chongqing Children's Hospital of Chongqing Medical University

Locations

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Chongqing Children's Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Yao Zhao

Role: CONTACT

86-23-6360-3083

Facility Contacts

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Yao Zhao

Role: primary

Other Identifiers

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2018-27

Identifier Type: -

Identifier Source: org_study_id

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