Body Weight-Based Interval Training in Sedentary Overweight and Obese Adults

NCT ID: NCT03524521

Last Updated: 2021-01-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

22 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-11-06

Study Completion Date

2021-01-08

Brief Summary

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Body-weight based interval training (IT) performed 3 times per week will lead to reductions in abdominal adiposity and reduce overall body fat percentage in overweight and obese sedentary adults more effectively than moderate intensity continuous training (MICT). Body-weight interval training will improve exercise capacity (peak VO2) in overweight/obese adults.

Detailed Description

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Participants will be randomly assigned to one of the two home-based exercise groups.

The MICT group is the standard care group and will be instructed to walk for 30 minutes, 5 days per week at a moderate intensity. The goal is to accumulate 150 minutes of continuous aerobic exercise each week. Participants will be instructed on the use of the Rating of Perceived Exertion (RPE) scale during baseline testing and will be instructed to reach an RPE of 12-16. A heart rate monitor will be worn to monitor exercise intensity. Heart rate should reach \~70% of maximal heart rate.

The IT group will perform 5 body-weight exercises in three progressive phases. During the first 2 weeks the circuit will be completed twice, 30 second intervals, 90 seconds of rest. The exercises will be performed on 3 days of the week with at least one day of rest between exercise days (ideally Monday, Wednesday, Friday). The number of repetitions will increase to a maximum of 4 while the interval and rest periods increase to a maximum of 45 seconds each. The total time spent performing intervals by week 8 will be 15 minutes. A 2 minute warm up and 3 minute cool down will be performed, such as jumping jacks or simply walking. A heart rate monitor will be used to measure exercise intensity. Heart rate should reach approximately 90% of heart rate max during the intervals. Participants will be instructed on the use of the Rating of Perceived Exertion scale during baseline testing and will be instructed to reach an RPE of ≥17 during the high intensity intervals.

Conditions

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Body Weight Changes Overweight and Obesity Physical Activity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Standard Walking

This arm is prescribed standard of care exercise prescription; 30 minutes of moderate intensity walking, 5 days/week.

Group Type ACTIVE_COMPARATOR

Standard of Care

Intervention Type BEHAVIORAL

Walking prescribed to meet current exercise guidelines; 150 minutes per week.

Interval Training

This arm is prescribed body-weight based interval training 3 days per week with progressive increase in exercise intervals and sets.

Group Type EXPERIMENTAL

Interval Training

Intervention Type BEHAVIORAL

Interval training is prescribed 3 days per week using 5 body weight exercises in a progressive fashion.

Interventions

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Interval Training

Interval training is prescribed 3 days per week using 5 body weight exercises in a progressive fashion.

Intervention Type BEHAVIORAL

Standard of Care

Walking prescribed to meet current exercise guidelines; 150 minutes per week.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Adults 18-65 years of age
* Willing and able to provide informed consent
* Sedentary, overweight and obese adults (\<90 minutes of moderate intensity exercise)
* BMI 25≤35
* Able to safely begin an exercise program
* Have a smartphone, and willing and able to download and use the Fitbit app

Exclusion Criteria

* Unable to provide informed consent.
* Known cardiovascular disease, or uncontrolled hypertension,
* Diagnosed type 1 or 2 diabetes
* Women who are pregnant or plan to become pregnant in the next 3-4 months
* Orthopedic injury/limitation or any other contraindications to exercise.
* Medications that cause weight gain (steroids, HIV-related medications, etc.), or glucose lowering medications
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Mayo Clinic

OTHER

Sponsor Role lead

Responsible Party

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Amanda R. Bonikowske

Senior Associate Consultant

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Amanda R Bonikowske

Role: PRINCIPAL_INVESTIGATOR

Mayo Clinic

Locations

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Mayo Clinic in Rochester

Rochester, Minnesota, United States

Site Status

Countries

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United States

Related Links

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Other Identifiers

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17-010163

Identifier Type: -

Identifier Source: org_study_id

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