Condensed Nanofat Grafting for Treatment of Androgenetic Alopecia

NCT ID: NCT03506503

Last Updated: 2021-02-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-02-27

Study Completion Date

2020-05-01

Brief Summary

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Nowadays, multiple treatment modalities have been applied clinically to treat androgenic alopecia, such as Follicular unit transplantation(FUT), finasteride, platelet-rich plasma injection(PRP), etc. In this clinical trial, the investigators aim to analyze the effect of nanofat grafting on treating androgenic alopecia in male.

Detailed Description

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The investigators will treat the hair loss area of a patient by processed nanofat grafting. The participants were asked to come back 1、3、6、9、12 months after treatment for further follow-up.

Before and after the treatment, the hair and follicular will be assessed subjectively by satisfaction assessment, dermatoscope.

Conditions

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Androgenic Alopecia

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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processed Nanofat grafting

processed autologous Nanofat will be injected into the area of the scalp with androgenic alopecia.

Group Type EXPERIMENTAL

Nanofat grafting

Intervention Type PROCEDURE

hair loss area will be treated by processed autologous Nanofat grafting

Interventions

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Nanofat grafting

hair loss area will be treated by processed autologous Nanofat grafting

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Male patients with androgenic alopecia aging from 18 to 50.
* No scars and wounds on the alopecia area.
* No skin disease or serious cardiovascular disease.
* Preoperative examinations remain healthy.

Exclusion Criteria

* Serious chronic heart, liver, kidney, blood system disease
* Allergic diseases, skin inflammation or wounds
* Alopecia but not androgenic alopecia
* Acute or chronic infection
* Take anticoagulant drugs
* Active vitiligo, psoriasis, systemic lupus erythematosus
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Jinan University Guangzhou

OTHER

Sponsor Role lead

Responsible Party

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Hongwei Liu

professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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the first affiliated hospital of Jinan University

Guangzhou, Guangdong, China

Site Status

Countries

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China

References

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Tonnard P, Verpaele A, Peeters G, Hamdi M, Cornelissen M, Declercq H. Nanofat grafting: basic research and clinical applications. Plast Reconstr Surg. 2013 Oct;132(4):1017-1026. doi: 10.1097/PRS.0b013e31829fe1b0.

Reference Type BACKGROUND
PMID: 23783059 (View on PubMed)

Won CH, Park GH, Wu X, Tran TN, Park KY, Park BS, Kim DY, Kwon O, Kim KH. The Basic Mechanism of Hair Growth Stimulation by Adipose-derived Stem Cells and Their Secretory Factors. Curr Stem Cell Res Ther. 2017;12(7):535-543. doi: 10.2174/1574888X12666170829161058.

Reference Type BACKGROUND
PMID: 28875863 (View on PubMed)

Gu Z, Li Y, Li H. Use of Condensed Nanofat Combined With Fat Grafts to Treat Atrophic Scars. JAMA Facial Plast Surg. 2018 Mar 1;20(2):128-135. doi: 10.1001/jamafacial.2017.1329.

Reference Type BACKGROUND
PMID: 28975248 (View on PubMed)

Other Identifiers

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2019004

Identifier Type: -

Identifier Source: org_study_id

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