Factors Contribute to Very Late Stent Thrombosis After New Generation DES Implantation in China

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

8476 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-01

Study Completion Date

2019-06-01

Brief Summary

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The investigators sought to identify and verify the potential correlates and mechanisms of Very Late Stent Thrombosis (VLST) after the implantation of new generation drug eluting steng in China from an analysis of multicenter registries.

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Detailed Description

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This study represents a patient-level pooled analysis of patients undergoing percutaneous coronary intervention with stent implantation for acute coronary syndrome. Multiple aspects including clinical, angiographic, procedural characteristics , intravascular imaging results and blood samples were collected at index PCI and the time of VLST or CAG during follow-up, in order to reveal the potential mechanisms or risk factors that contribute to the development of VLST.

Conditions

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Stent Thrombosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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derivation cohort

no interventions will be administrated

No interventions assigned to this group

validation cohort

no interventions will be administrated

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients\>18y,admitted for acute coronary syndrome,successfully underwent PCI with at least one stent, sign informed consent.

Exclusion Criteria

* Expected lifetime was less than 1 year for any severe disease(such as tumor,severe respiratory failure et al). There is a surgical plan for important organs within 1 year after surgery and anti-platelet drugs should be discontinued. Refusing to sign informed consent.Died prior to discharge. Poor compliance, unable to participate in regular follow-up.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No