Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
20 participants
INTERVENTIONAL
2010-01-31
2011-10-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Stent Thrombosis
Consecutive patients with stent thrombosis with stent strut assessment by OCT
OCT guided PCI
OCT guided PCI. Only thrombectomy in case of negative OCT findings (other than uncovered struts).
Controls
Control subjects without stent thrombosis from the RHR OCT database
OCT guided medical therapy
OCT guided medical therapy. Tailored antiplatelet therapy.
Interventions
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OCT guided PCI
OCT guided PCI. Only thrombectomy in case of negative OCT findings (other than uncovered struts).
OCT guided medical therapy
OCT guided medical therapy. Tailored antiplatelet therapy.
Eligibility Criteria
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Inclusion Criteria
* previous PCI with DES and a definite late or very late coronary ST
Exclusion Criteria
* Late and very late ST of BMS.
* Absence of informed consent.
* Age less than 18 years.
* Creatinine values greater than 2.5 g/dl (this is to avoid the negative effects related to the contrast medium necessary to perform the OCT evaluation).
18 Years
ALL
No
Sponsors
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Careggi Hospital
OTHER
Responsible Party
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David Antoniucci
Head Division of Invasive Cardiology
Principal Investigators
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David Antoniucci, MD
Role: STUDY_CHAIR
Careggi Hospital, Division of Invasive Cardiology
Francesco Prati, MD
Role: PRINCIPAL_INVESTIGATOR
Rome Heart Research
Locations
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Careggi Hospital, Department of Hearth and Vessels
Florence, , Italy
Countries
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References
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Parodi G, La Manna A, Di Vito L, Valgimigli M, Fineschi M, Bellandi B, Niccoli G, Giusti B, Valenti R, Cremonesi A, Biondi-Zoccai G, Prati F. Stent-related defects in patients presenting with stent thrombosis: differences at optical coherence tomography between subacute and late/very late thrombosis in the Mechanism Of Stent Thrombosis (MOST) study. EuroIntervention. 2013 Dec;9(8):936-44. doi: 10.4244/EIJV9I8A157.
Other Identifiers
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MOST Study
Identifier Type: -
Identifier Source: org_study_id
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