Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
35 participants
OBSERVATIONAL
2016-02-29
2018-01-31
Brief Summary
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Detailed Description
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1. To use OCT to determine the type of plaque (plaque rupture, plaque erosion or calcified nodule) most associated with the presence and severity of MVO (as measured by IMR and cardiac MRI).
2. To use OCT to investigate the relationship between the extent of tissue protrusion and the amount of residual stent thrombus with the presence and severity of MVO (as measured by IMR and cardiac MRI).
Conditions
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Study Design
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CASE_ONLY
PROSPECTIVE
Study Groups
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STEMI patients
The patients presenting with a STEMI and undergoing PPCI will be screened and approached to participate in this study.
All patients to do Optical Coherence Tomography (OCT), Index of Microcirculatory Resistance (IMR) and Cardiac MRI.
Optical coherence tomography (OCT)
Special camera to study part of your heart that was affected
Index of microcirculatory resistance (IMR)
Special wire to study part of your heart that was affected
Cardiac MRI
Special scanner if the heart to assess the damage of your heart
Interventions
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Optical coherence tomography (OCT)
Special camera to study part of your heart that was affected
Index of microcirculatory resistance (IMR)
Special wire to study part of your heart that was affected
Cardiac MRI
Special scanner if the heart to assess the damage of your heart
Eligibility Criteria
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Inclusion Criteria
2. \< 12 hours of onset of chest pain.
3. Ability to provide informed consent
Exclusion Criteria
2. Cardiac arrest or cardiogenic shock
3. Inability to advance the OCT catheter or to obtain good image quality
4. Ostial lesions
5. Significant renal impairment
6. Contraindications for cardiac MRI
7. Contraindication for adenosine (for IMR measurement)
21 Years
99 Years
ALL
No
Sponsors
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National Heart Centre Singapore
OTHER
Responsible Party
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Principal Investigators
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Derek Hausenloy
Role: PRINCIPAL_INVESTIGATOR
National Heart Centre Singapore
Locations
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National Heart Centre Singapore
Singapore, Singapore, Singapore
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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2015/3034
Identifier Type: -
Identifier Source: org_study_id
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