Optical Coherence Tomography Guided Percutaneous Coronary Intervention for Drug-eluting In-stent Restenosis
NCT ID: NCT03809754
Last Updated: 2019-01-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
240 participants
INTERVENTIONAL
2019-03-01
2020-09-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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OCT-guided PCI
Percutaneous Coronary Intervention under OCT
After randomization, subjects receive primary PCI under the guiding of OCT
Angiography-guided PCI
Percutaneous Coronary Intervention under Angiography
After randomization, subjects receive primary PCI under the guiding of angiography
Interventions
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Percutaneous Coronary Intervention under OCT
After randomization, subjects receive primary PCI under the guiding of OCT
Percutaneous Coronary Intervention under Angiography
After randomization, subjects receive primary PCI under the guiding of angiography
Eligibility Criteria
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Inclusion Criteria
* Patients with angina or evidence of myocardial ischaemia
* Patients with restenotic lesions in a previously DES area of a coronary artery
* Patients suitable to receive any types of percutaneous coronary intervention (including balloon angioplasty and stent implantation)
* The stent diameter of DES-ISR is 2.5mm to 4.0mm
* Target lesion length \< 30mm
* Target lesion stenosis ≥ 70% diameter stenosis on visual assessment, or ≥ 50% diameter stenosis and with evidence of myocardial ischaemia ischemic
Exclusion Criteria
* Patients with evidence of extensive thrombosis in the target vessel
* Patients with left main coronary artery disease
* Patients with cardiogenic shock, left ventricular ejection fraction \< 40%,significant renal dysfunction and severe heart valve disease
* Patients who had cerebral stroke within 6 months before PCI
* Patients with a life expectancy \< 1 year
* Patients not able to adhere to follow-up visits
18 Years
ALL
No
Sponsors
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Chinese PLA General Hospital
OTHER
Responsible Party
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Yun Dai Chen
Professor
Principal Investigators
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Yundai Chen
Role: PRINCIPAL_INVESTIGATOR
Chinese PLA General Hospital
Locations
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Yundai Chen
Beijing, , China
Countries
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Central Contacts
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References
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Han Y, Yuan X, Wang W, Wang N, Zhang Y, Jing J, Chen Y, Gao L. Clinical Significance of Optical Coherence Tomography-Guided Percutaneous Coronary Intervention for In-Stent Restenosis Within Drug-Eluting Stents: Impact on Patient Outcomes. J Am Heart Assoc. 2024 Nov 5;13(21):e033954. doi: 10.1161/JAHA.123.033954. Epub 2024 Nov 4.
Other Identifiers
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Z171100001017158
Identifier Type: -
Identifier Source: org_study_id
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