Seoul National University Pituitary Disease Cohort Study

NCT ID: NCT03474601

Last Updated: 2020-03-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

1600 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-03-15

Study Completion Date

2025-02-14

Brief Summary

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The purpose of this study is to investigate the treatment and natural history of pituitary disease. We have a longstanding interest in pituitary disease including acromegaly, central diabetes insipidus, and nonfunctioning pituitary adenoma. We will continue to follow patients and recruit new patients for treatment and follow-up. Blood and pituitary tumor tissue (when available through clinical care) will be saved for future analyses related to pituitary disease.

Detailed Description

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Subjects for this study will be recruited if they are:

1. Adults, male or female aged 18 years or older
2. Have been diagnosed with pituitary diseases

Conditions

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Pituitary Disease Pituitary Incidentaloma Acromegaly Central Diabetes Insipidus Pituitary Stalk Compression Hyperprolactinaemia Cushing's Disease Pituitary Tumor Prolactinoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Acromegaly

Patients diagnosed with acromegaly

Dynamic hormone study and Magnetic resonance imaging

Intervention Type OTHER

1. Medical history
2. Imaging examination including brain magnetic resonance imaging
3. Blood (Basal hormone study and follow-up study) and pituitary tumor tissue

Cushing's disease

Patients diagnosed with Cushing's disease

Dynamic hormone study and Magnetic resonance imaging

Intervention Type OTHER

1. Medical history
2. Imaging examination including brain magnetic resonance imaging
3. Blood (Basal hormone study and follow-up study) and pituitary tumor tissue

Hyperprolactinemia/prolactinomas

Patients diagnosed with hyperprolactinemia/prolactinoma

Dynamic hormone study and Magnetic resonance imaging

Intervention Type OTHER

1. Medical history
2. Imaging examination including brain magnetic resonance imaging
3. Blood (Basal hormone study and follow-up study) and pituitary tumor tissue

Pituitary stalk lesions

Patients diagnosed with pituitary stalk lesions

Dynamic hormone study and Magnetic resonance imaging

Intervention Type OTHER

1. Medical history
2. Imaging examination including brain magnetic resonance imaging
3. Blood (Basal hormone study and follow-up study) and pituitary tumor tissue

Nonfunctioning pituitary adenomas

Patients diagnosed with nonfunctioning pituitary adenomas

Dynamic hormone study and Magnetic resonance imaging

Intervention Type OTHER

1. Medical history
2. Imaging examination including brain magnetic resonance imaging
3. Blood (Basal hormone study and follow-up study) and pituitary tumor tissue

Central diabetes insipidus

Patients diagnosed with central diabetes insipidus

Dynamic hormone study and Magnetic resonance imaging

Intervention Type OTHER

1. Medical history
2. Imaging examination including brain magnetic resonance imaging
3. Blood (Basal hormone study and follow-up study) and pituitary tumor tissue

Craniopharyngioma

Patients diagnosed with craniopharyngiomas

Dynamic hormone study and Magnetic resonance imaging

Intervention Type OTHER

1. Medical history
2. Imaging examination including brain magnetic resonance imaging
3. Blood (Basal hormone study and follow-up study) and pituitary tumor tissue

Others

Patients diagnosed with other suprasellar/parasellar lesions

Dynamic hormone study and Magnetic resonance imaging

Intervention Type OTHER

1. Medical history
2. Imaging examination including brain magnetic resonance imaging
3. Blood (Basal hormone study and follow-up study) and pituitary tumor tissue

Interventions

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Dynamic hormone study and Magnetic resonance imaging

1. Medical history
2. Imaging examination including brain magnetic resonance imaging
3. Blood (Basal hormone study and follow-up study) and pituitary tumor tissue

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Subjects for this study will be recruited if they are:

1. Adults, male or female aged 18 years or older
2. diagnosed with pituitary diseases such as acromegaly, Cushing's disease, hyperprolactinemia, nonfunctioning pituitary adenoma, pituitary stalk lesions, central diabetes insipidus, and craniopharyngiomas

Exclusion Criteria

* Patients who do not agree with the study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Seoul National University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Jung Hee Kim

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jung Hee Kim, M.D

Role: PRINCIPAL_INVESTIGATOR

Seoul National University Hospital

Locations

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Seoul National University Hospital

Seoul, , South Korea

Site Status RECRUITING

Countries

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South Korea

Central Contacts

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Jung Hee Kim, M.D

Role: CONTACT

82-2-2072-4073

Facility Contacts

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Jung Hee Kim, M.D

Role: primary

Other Identifiers

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1503-040-654

Identifier Type: -

Identifier Source: org_study_id

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