The Effect of Bariatric Surgery to Central Sensitization

NCT ID: NCT03460691

Last Updated: 2018-03-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-03-09

Study Completion Date

2018-12-09

Brief Summary

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Nowadays obesity is emerging as a very common health problem. It has been shown in various studies that obesity may be an important risk factor for the onset and progression of knee osteoarthritis (OA). The aim of this study is to determine the effects of bariatric surgery on knee pain, loss of function, quality of life and central sensitization.

Detailed Description

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Weight loss in patients with knee OA reduces pain and provides functional improvement. It has been shown that bariatric surgery combined with diet and exercise changes have positive effects on weight loss, knee pain and function.

Neuropathic pain is a disease that affects the somatosensory system or pain that results in a lesion. It has been reported that neuropathic pain is more frequently seen in patients with high body mass index.

The hyperreactivity of the central nervous system (CNS) plays an important role in the chronic pain of OA patients. It has been shown that CNS becomes hypersensitive in people with chronic OA pain and central sensitization phenomenon plays an important role in pain complaints reported by these patients.

The aim of this study is to determine the effects of bariatric surgery on knee pain, loss of function, quality of life and central sensitization.

Conditions

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Bariatric Surgery Central Sensitization

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Group 1

Group 1:patients who will undergo the bariatric surgery

Bariatric surgery

Intervention Type PROCEDURE

Bariatric surgery will done to the patients who were morbid obesity

Interventions

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Bariatric surgery

Bariatric surgery will done to the patients who were morbid obesity

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients decided to undergo bariatric surgery
* Patients with knee pain more than 3 months.

Exclusion Criteria

* Patients with mental impairment,
* Patients with inflammatory rheumatic disease,
* Patients who had previously undergone knee surgery
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bursa Yuksek Ihtisas Training and Research Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Dr. Burcu Metin Ökmen

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Burcu Metin Ökmen

Role: PRINCIPAL_INVESTIGATOR

Bursa Yuksek Ihtisas Training and Research Hospital

Central Contacts

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Burcu Metin Ökmen, M.D.

Role: CONTACT

+902242955000

Other Identifiers

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2011-KAEK-2017-19/20

Identifier Type: -

Identifier Source: org_study_id

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