Passive Leg Raising - an Important Diagnostic Manoeuvre
NCT ID: NCT03454802
Last Updated: 2021-09-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
11 participants
INTERVENTIONAL
2018-09-01
2020-10-01
Brief Summary
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The protocol entails the measurement of stroke volume (SV) at baseline (semirecumbent patient position), during PLR and after returning to semirecumbent position. Simultaneously blood pressure (BP), pulse rate (PR), pulse oximetric saturation (SpO2) and ECG are recorded. The procedure is performed in ten normal subjects, ten patients recruited in the cardiology outpatient department and ten critically ill patients under analgosedation in the ICU.
Analysis includes changes in measured variables and heart rate variability in the frequency domain during the three phases of the experiment.
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
SEQUENTIAL
BASIC_SCIENCE
SINGLE
Study Groups
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Normal subjects
Normal subjects 'Passive Leg Raising'
Passive Leg Raising
See above
ICU patients
ICU patients 'Passive Leg Raising'
Passive Leg Raising
See above
Cardiac Outpatients
Cardiac Outpatients 'Passive Leg Raising'
Passive Leg Raising
See above
Interventions
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Passive Leg Raising
See above
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
80 Years
ALL
Yes
Sponsors
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Edwards Lifesciences
INDUSTRY
Region MidtJylland Denmark
OTHER
Responsible Party
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Soren Sondergaard
Senior Consultant, MD, PhD
Principal Investigators
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Peter Toft, MD
Role: STUDY_CHAIR
Head of Centre of Planned Surgery, Silkeborg Regional Hospital
Locations
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Regionshospitalet Silkeborg
Silkeborg, Central Jutland, Denmark
Countries
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References
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Monnet X, Rienzo M, Osman D, Anguel N, Richard C, Pinsky MR, Teboul JL. Passive leg raising predicts fluid responsiveness in the critically ill. Crit Care Med. 2006 May;34(5):1402-7. doi: 10.1097/01.CCM.0000215453.11735.06.
Other Identifiers
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619909
Identifier Type: -
Identifier Source: org_study_id
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