Functional Magnetic Resonance Imaging (fMRI) Exploration of Neurocognitive Processes Involved in Food Addiction (FA) in Obese Patients: Towards New Phenotypic Markers for an Optimized Care Pathway
NCT ID: NCT03454711
Last Updated: 2023-08-01
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2/PHASE3
47 participants
INTERVENTIONAL
2018-04-26
2021-09-08
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
OTHER
NONE
Study Groups
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Patient with food addcitions
Patients (20) will be selected from the Yale Food Addiction Scale (YFAS): a validated screening of FA questionnaire.
Three clinical visits will be realized in less than two months
fMRI
Brain MRI
Indirect calorimetry
Resting energy expenditure
Bioimpedance
Measurement of body composition
Lipid profile, glucose, HBA1c, metabolomic analysis
Blood sample
YFAS questionnaire, Binge Eating Scale, Hospital Anxiety and Depression (HAD) scale, hedonic evaluation test (liking)
Questionnaires to characterize eating habits and depression
Patients without food addictions
Patients (20) will be selected from the Yale Food Addiction Scale (YFAS): a validated screening of FA questionnaire.
Three clinical visits will be realized in less than two months
fMRI
Brain MRI
Indirect calorimetry
Resting energy expenditure
Bioimpedance
Measurement of body composition
Lipid profile, glucose, HBA1c, metabolomic analysis
Blood sample
YFAS questionnaire, Binge Eating Scale, Hospital Anxiety and Depression (HAD) scale, hedonic evaluation test (liking)
Questionnaires to characterize eating habits and depression
Interventions
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fMRI
Brain MRI
Indirect calorimetry
Resting energy expenditure
Bioimpedance
Measurement of body composition
Lipid profile, glucose, HBA1c, metabolomic analysis
Blood sample
YFAS questionnaire, Binge Eating Scale, Hospital Anxiety and Depression (HAD) scale, hedonic evaluation test (liking)
Questionnaires to characterize eating habits and depression
Eligibility Criteria
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Inclusion Criteria
* right-handed
* grade 1 and 2 obesity
* aged between 20 and 50
* no other addictions including smoking
* no contraindications to fMRI
* affiliated to French Social Security
* having given a written informed consent
Exclusion Criteria
* addiction to alcohol or other psychoactive substances
* daily smoker
* sleep Apnea Syndrome paired
* psychotic psychiatric disorders
* history of bariatric surgery
* medical care in the nutrition unit
* inability to comprehend or complete questionnaires
* pregnant or breastfeeding woman
* persons subject to major legal protection (safeguarding justice, guardianship, trusteeship), persons deprived of liberty.
30 Years
50 Years
FEMALE
No
Sponsors
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Institut NuMeCan, INRAE 1341
UNKNOWN
Rennes University Hospital
OTHER
Responsible Party
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Principal Investigators
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David Val-Laillet, MSc, PhD, HDR
Role: STUDY_DIRECTOR
Institut NuMeCan, INRA 1341, INSERM 1241, Université de Rennes 1
Locations
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CHU de Rennes
Rennes, , France
Countries
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Other Identifiers
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2017-A01269-44
Identifier Type: OTHER
Identifier Source: secondary_id
35RC17_8949_AddictO
Identifier Type: -
Identifier Source: org_study_id
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