Cognitive Processes Study in Obese Women With and Without Eating Disorders

NCT ID: NCT01948414

Last Updated: 2025-12-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

108 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-07-31

Study Completion Date

2015-06-30

Brief Summary

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The P300 is one of the cognitive wave of the Event-Related Potential (ERP) that is used to investigate the cognitive process. The P300 component are accepted as electro-physiological markers of neuropsychiatric disorders like alcoholism or drug addiction.

Recent scientific data suggest that eating disorders, leading to weight gain and obesity, will be similar of those of drug addiction: it is the incentive sensitization theory that implicates the dopaminergic reward system.

The aim of this cross-sectional study is to investigate the alteration of P300 auditory ERP in obese women with eating disorders in comparison with obese and lean women without eating disorders.

Detailed Description

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Conditions

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Hyperalimentation and Obesity

Keywords

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Obesity Hyperalimentation Event-Related Potential P300

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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obese women with eating disorders

Obese women with eating disorders : women with BMI higher or equal 35 and disinhibition score to TFEQ strictly higher to 8

Group Type OTHER

electroencephalography

Intervention Type PROCEDURE

Blood sampling

Intervention Type BIOLOGICAL

Questionnaires regarding eating habits (TFEQ, EDI) and anxiety/depression (HAD)

Intervention Type BEHAVIORAL

Obese women without eating desorders

Obese women without eating disorders : women with BMI higher or equal to 35 and disinhibition score to TFEQ lower or equal to 8

Group Type OTHER

electroencephalography

Intervention Type PROCEDURE

Blood sampling

Intervention Type BIOLOGICAL

Questionnaires regarding eating habits (TFEQ, EDI) and anxiety/depression (HAD)

Intervention Type BEHAVIORAL

Lean women

Lean women : women with BMI from 18.5 to 24.5 and disinhibition score to Three-Factor Eating Questionnaire (TFEQ)lower or equal to 8

Group Type OTHER

electroencephalography

Intervention Type PROCEDURE

Blood sampling

Intervention Type BIOLOGICAL

Questionnaires regarding eating habits (TFEQ, EDI) and anxiety/depression (HAD)

Intervention Type BEHAVIORAL

Interventions

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electroencephalography

Intervention Type PROCEDURE

Blood sampling

Intervention Type BIOLOGICAL

Questionnaires regarding eating habits (TFEQ, EDI) and anxiety/depression (HAD)

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* women
* Aged from 20 to 55 years
* Fasting glycemia under 7mmol/L
* Lean women : women with BMI from 18.5 to 24.5 and disinhibition score to Three-Factor Eating Questionnaire (TFEQ)lower or equal to 8
* Obese women without eating disorders : women with BMI higher or equal to 35 and disinhibition score to TFEQ lower or equal to 8
* Obese women with eating disorders : women with BMI higher or equal 35 and disinhibition score to TFEQ strictly higher to 8

Exclusion Criteria

* Subject not in compliance with the recommendations of French National Law in force
* Medical history of diabetes and surgery history of obesity
* Drug use that could affect the ERP recording
* Hospital Anxiety and Depression scale : evaluation subscale (anxiety and/or depression) strictly higher to 11
Minimum Eligible Age

20 Years

Maximum Eligible Age

55 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Hospices Civils de Lyon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Emmanuel DISSE, Pratician

Role: PRINCIPAL_INVESTIGATOR

CRNH Rhône-Alpes /CENS Centre Européen pour la Nutrition et la Santé - Centre Hospitalier Lyon Sud

Locations

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CRNH Rhône-Alpes /CENS Centre Européen pour la Nutrition et la Santé Centre Hospitalier Lyon Sud - Pavillon médical 165, chemin du Grand Revoyet

Pierre-Bénite, , France

Site Status

Countries

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France

References

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Iceta S., Benoit J., Lambert-Porcheron S., Peyrat J., Cristini P., Poulet E., Laville M., Disse E. Obésité, addiction et prise alimentaire : étude des potentiels évoqués cognitifs. Nutrition Clinique et Métabolisme. 2018;32:231-338 (Section " 232 Congrès ", résumé CO09). doi:10.1016/j.nupar.2018.09.007 / 2018.09.008

Reference Type RESULT

Related Links

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Other Identifiers

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2012.784

Identifier Type: -

Identifier Source: org_study_id