Mechanized Instrumentation for Endodontic Treatment of Primary Teeth

NCT ID: NCT03453658

Last Updated: 2021-03-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

151 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-11-08

Study Completion Date

2021-01-28

Brief Summary

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Mechanized instrumentation systems stand out amongst various devices used in modern Endodontics. Its use in Pediatric Dentistry, its action in primary teeth, has been in the center of many discussions and laboratory studies. Nevertheless, up to now, a lack of clinical studies on this issue can be found. Our objective is to conduct a double blinded, 2 years follow up clinical trial to compare the success of endodontic treatment in primary teeth using mechanized reciprocating instrumentation to the use of manual instrumentation.

Detailed Description

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With the approval of the Ethics Committee of University of São Paulo, after clinical and radiographic examination, patients in search for endodontic treatment in primary teeth will be invited to take part in the study. The participants of the study will be randomized to one of two groups (manual or reciprocating instrumentation). Endodontic treatment will be held by a specialist according to the randomized group. A blinded examiner will proceed one week, 3 months, 6 months, 12 months and 24 months follow ups. Clinical and radiographic conditions of endodontic treatments will be analyzed to classify them as Success or Failure. The unit of analysis will be the teeth; hence, each participant may have more than one tooth included in the study. The randomization will be performed considering the tooth. Data analysis will consider the cluster nature of the sample.

The primary outcome of the study will be the success rates according to the groups. The longevity of treatments will be evaluated by estimating survival rates by Kaplan-Meier and Cox regression. The differences between survival rates of both groups will be through Cox regression adjusted for the cluster nature of the sample (more than one tooth per participant), considering a level of significance of 5%.

Conditions

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Endodontic Treatment of Primary Teeth

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized, single-blind, controlled clinical trial with two parallel arms.
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors
The outcomes assessor will be a different examiner who will be unaware of the allocated group.

Study Groups

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Manual instrumentation

Manual instrumentation: Endodontic treatment will be performed with the use of conventional endodontic manual files.

Group Type ACTIVE_COMPARATOR

Manual instrumentation

Intervention Type PROCEDURE

Manual conventional files will be used in endodontic treatment of primary teeth

Reciprocating instrumentation

Mechanized instrumentation: Endodontic treatment will be performed with the use of reciprocating mechanized files. The files are activated by an engine that produces reciprocating movements.

Group Type EXPERIMENTAL

Reciprocating Instrumentation

Intervention Type PROCEDURE

Reciprocating files system will be used in endodontic treatment of primary teeth.

Interventions

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Manual instrumentation

Manual conventional files will be used in endodontic treatment of primary teeth

Intervention Type PROCEDURE

Reciprocating Instrumentation

Reciprocating files system will be used in endodontic treatment of primary teeth.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Primary molar teeth with necessity of endodontic treatment.
* Patients whose parents or guardians consent to their participation in the study

Exclusion Criteria

Teeth presenting one of the following:

* Resorption of more than 2/3 of the root
* Destruction of the crypt of the permanent successor
* Pulp chamber floor drilling.
* Presence of internal resorption
Minimum Eligible Age

3 Years

Maximum Eligible Age

9 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Sao Paulo

OTHER

Sponsor Role lead

Responsible Party

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Fausto Medeiros Mendes

Associate professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Renata Marques, PhD Student

Role: PRINCIPAL_INVESTIGATOR

University of Sao Paulo

Locations

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School of Dentistry, University of Sao Paulo

São Paulo, , Brazil

Site Status

Countries

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Brazil

References

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Reference Type BACKGROUND
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Reference Type BACKGROUND
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Reference Type BACKGROUND
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Reference Type BACKGROUND
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Reference Type BACKGROUND
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Reference Type BACKGROUND
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Nobrega DF, Fernandez CE, Del Bel Cury AA, Tenuta LM, Cury JA. Frequency of Fluoride Dentifrice Use and Caries Lesions Inhibition and Repair. Caries Res. 2016;50(2):133-40. doi: 10.1159/000444223. Epub 2016 Mar 19.

Reference Type BACKGROUND
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Reference Type BACKGROUND
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Reference Type BACKGROUND
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Prabhakar AR, Yavagal C, Dixit K, Naik SV. Reciprocating vs Rotary Instrumentation in Pediatric Endodontics: Cone Beam Computed Tomographic Analysis of Deciduous Root Canals using Two Single-file Systems. Int J Clin Pediatr Dent. 2016 Jan-Mar;9(1):45-9. doi: 10.5005/jp-journals-10005-1332. Epub 2016 Apr 22.

Reference Type BACKGROUND
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Reference Type BACKGROUND
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Other Identifiers

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FOUSP2912

Identifier Type: -

Identifier Source: org_study_id

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