A Study of the Effect of High Altitudes on Physiological and Metabolic Markers in Adults Living at Qinghai-Tibet Plateau for Work Purpose

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

160 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-07-22

Study Completion Date

2019-07-01

Brief Summary

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This ambispective cohort study aims to evaluate the effect of high altitudes environment on human's physiological and metabolic markers, specific markers of main human systems, and incidence rate and severity of chronic mountain sickness (CMS).

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Detailed Description

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Qinghai-Tibet plateau is a high altitudes area with average 3,000-5,000 meters height in China. As the partial pressure of oxygen in inspired air falls with increasing terrestrial elevation above sea level, many physiological variables in human body could be affected by this hypobaric hypoxic environment. Up to date, there are no large scale clinical trials assessing these changes in chinese population. The study here would like to provide the newest medical information on the changes of physiological variables and correlation between specific risk factors in chinese adults living at high altitudes for work purpose.

Conditions

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Residence or Prolonged Visit at High Altitude as the Cause of Mountain Sickness

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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Adults Living at Qinghai-Tibet Plateau for Work Purpose

Qinghai-Tibet Plateau is a high altitude area in which human would be exposed in chronic hypoxia environment.

Chronic hypoxic environment

Intervention Type OTHER

Chronic hypoxic environment. Since the partial pressure of oxygen in inspired air falls with increasing terrestrial elevation above sea level, many physiological variables in adults would be affected by the chronic hypoxia environment.

Interventions

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Chronic hypoxic environment

Chronic hypoxic environment. Since the partial pressure of oxygen in inspired air falls with increasing terrestrial elevation above sea level, many physiological variables in adults would be affected by the chronic hypoxia environment.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Be provided verbal or written informed consent;
* Men and women ≥ 30 and ≤ 65 years of age;
* Adults living at Qinghai-Tibet Plateau for Work Purpose, and the altitude of residence is more than 2,500 meters;
* Providing electronical or paper medical examination reports which conducted in 2016.