Effects of Core Stability Training on Gait in Multiple Sclerosis Patients

NCT ID: NCT03442049

Last Updated: 2018-02-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

68 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-01-01

Study Completion Date

2016-05-01

Brief Summary

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Gait and mobility are among the functions frequently affected in Multiple Sclerosis (MS) and have a negative impact on quality of life. Strength losses in lower limb muscles, ataxia, sensory problems and fatigue are the most important reasons of walking problems in patients with MS. In addition to loss of strength and tonus problems, especially biomechanical disorders can be seen on foot and this problem affects gatin and balance negatively. The stabilizing muscles, defined as the "core" region and enveloping the body like a corset, are active in the context of postural preparation prior to lower extremity movements and stabilize for the limb movements to be performed. The aim of this study was to investigate the effects of spinal stabilization exercises on walking performance, fatigue, plantar pressure distribution, balance, muscle strength and quality of life in patients with Multiple Sclerosis.

Detailed Description

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Conditions

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Multiple Sclerosis Gait Disorders, Neurologic

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized Controlled Trial
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Study group

Spinal stabilization exercises in addition to home exercise program

Group Type EXPERIMENTAL

Physiotherapy - Study group

Intervention Type OTHER

Study group : In addition to home program spinal stabilization exercises

Control Group

Home exercise program

Group Type ACTIVE_COMPARATOR

Physiotherapy - control group

Intervention Type OTHER

Home exercise program

Interventions

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Physiotherapy - Study group

Study group : In addition to home program spinal stabilization exercises

Intervention Type OTHER

Physiotherapy - control group

Home exercise program

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Older than 18 years old
* EDSS score is between 3-5,5
* Patients who did not take corticosteroid therapy within three months
* Patients who get at least 24 points from the Mini Mental Test were included in the study.

Exclusion Criteria

* Patients who had an acute MS attack or had an attack within the last three months.
* An orthopedic or systemic problem that would prevent participation in exercises
* Patients who were using walking orthoses or walking aids were not included in the study.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hacettepe University

OTHER

Sponsor Role lead

Responsible Party

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Baris Cetin

Research Assisstant

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Bethoux F. Gait disorders in multiple sclerosis. Continuum (Minneap Minn). 2013 Aug;19(4 Multiple Sclerosis):1007-22. doi: 10.1212/01.CON.0000433286.92596.d5.

Reference Type BACKGROUND
PMID: 23917098 (View on PubMed)

Givon U, Zeilig G, Achiron A. Gait analysis in multiple sclerosis: characterization of temporal-spatial parameters using GAITRite functional ambulation system. Gait Posture. 2009 Jan;29(1):138-42. doi: 10.1016/j.gaitpost.2008.07.011. Epub 2008 Oct 31.

Reference Type BACKGROUND
PMID: 18951800 (View on PubMed)

Freeman JA, Gear M, Pauli A, Cowan P, Finnigan C, Hunter H, Mobberley C, Nock A, Sims R, Thain J. The effect of core stability training on balance and mobility in ambulant individuals with multiple sclerosis: a multi-centre series of single case studies. Mult Scler. 2010 Nov;16(11):1377-84. doi: 10.1177/1352458510378126. Epub 2010 Aug 10.

Reference Type BACKGROUND
PMID: 20699285 (View on PubMed)

Hides J, Wilson S, Stanton W, McMahon S, Keto H, McMahon K, Bryant M, Richardson C. An MRI investigation into the function of the transversus abdominis muscle during "drawing-in" of the abdominal wall. Spine (Phila Pa 1976). 2006 Mar 15;31(6):E175-8. doi: 10.1097/01.brs.0000202740.86338.df.

Reference Type BACKGROUND
PMID: 16540858 (View on PubMed)

Freeman J, Fox E, Gear M, Hough A. Pilates based core stability training in ambulant individuals with multiple sclerosis: protocol for a multi-centre randomised controlled trial. BMC Neurol. 2012 Apr 5;12:19. doi: 10.1186/1471-2377-12-19.

Reference Type BACKGROUND
PMID: 22480437 (View on PubMed)

Other Identifiers

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GO 14/633

Identifier Type: -

Identifier Source: org_study_id

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