Effects of a Circuit Training on Balance in Persons With Multiple Sclerosis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

52 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-02-26

Study Completion Date

2025-05-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The aim of the study is to evaluate the effects of a circuit training rehabilitation program on the perceived impact of fatigue in daily life situations and on gait and balance. Half of the participants will follow the circuit training program, while the other half will follow usual care rehabilitation programs.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Effect of High Intensity Training on Motor and Cognitive Functions

NCT06219304

Multiple Sclerosis

RECRUITING NA

How Does Strength Training and Balance Training Affect Gait Function and Fatigue in Patients With Multiple Sclerosis?

NCT02870023

Multiple Sclerosis

COMPLETED NA

Task-oriented Circuit Class Training in Multiple Sclerosis Subjects

NCT01464749

Multiple Sclerosis

COMPLETED NA

Stabilometric Assessment of Balance Recovery in Persons With Multiple Sclerosis

NCT02131285

Multiple Sclerosis

COMPLETED NA

Sensori-motor Integration Training in Multiple Sclerosis

NCT01040117

Relapsing-remitting Multiple Sclerosis

COMPLETED EARLY_PHASE1

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Approximately 80% of Persons with Multiple Sclerosis rates fatigue among the three most disabling symptoms. Aerobic, balance and strength training have already been proved effective in rehabilitation, especially for Persons with Multiple Sclerosis. Fifty-two Persons with Multiple Sclerosis will be randomly allocated to an experimental group or to a control group following usual care rehabilitation programs. Experimental group will follow a circuit training rehabilitation program which combines high intensity aerobic training with balance and strength training. The study aims to verify the effects of the circuit training program on fatigue and on balance in different contexts with respect to usual care rehabilitation programs and to investigate effects of rehabilitation on immunological markers.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Multiple Sclerosis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Circuit Training

Structured intervention to improve aerobic capacity, balance and strength

Group Type EXPERIMENTAL

Circuit Training

Intervention Type OTHER

20 minutes of High Intensity Aerobic Training (HI) on treadmill: 2 minutes warm up + 4x 4 minutes HI+ 2 minutes of active recovery; 10 minutes of dynamic balance training; 10 minutes of functional strength training.

Usual Care

Unstructured intervention to improve mobility and balance

Group Type ACTIVE_COMPARATOR

Usual Care

Intervention Type OTHER

Exercises aimed at improving mobility and balance

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Circuit Training

20 minutes of High Intensity Aerobic Training (HI) on treadmill: 2 minutes warm up + 4x 4 minutes HI+ 2 minutes of active recovery; 10 minutes of dynamic balance training; 10 minutes of functional strength training.

Intervention Type OTHER

Usual Care

Exercises aimed at improving mobility and balance

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Definite diagnosis of Multiple Sclerosis (Polman criteria);
* No relapses in the previous three months;
* Expanded Disability Status Scale \< 6,5;
* Able to walk 20 meter with or without an assistive device;
* Able to stand for 30 second without aid;
* MiniMental State Examination \>20;

Exclusion Criteria

* Unable to understand the aim of the study or unable to sign the informed consent form;
* Subjects following a steroidal drug therapy or assuming drugs affecting cardiac function;
* Subjects with psychiatric disorders;
* Subjects with cardiovascular diseases for whom aerobic training is forbidden;

Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No