Prevalence of H.Pylori in Patients With Acne Vulgaris Acne Vulgaris

NCT ID: NCT03411733

Last Updated: 2018-05-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

90 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-03-01

Study Completion Date

2018-03-01

Brief Summary

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The objective of the study is to investigate prevalence of H.Pylori infection among acne vulgaris patients.

Detailed Description

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The study included patients with acne vulgaris and healthy control participants. The study recruited both sexes, all grades of acne, adolescents and young adults.

All patients were subjected to complete history, general and skin examination Acne vlugaris Patients were classified into mild, moderate and severe according to the classification of American Academy of dermatology for acne vulgaris.

Detection of H. pylori infection:

Blood and stool samples were taken from each participant and was directly transferred to laboratory for detection of H. Pylori antigen and antibody.

An enzyme-linked immune sorbent assay (ELISA) was used for quantitative assessment of IgG antibodies against H.Pylori in human serum.

A monoclonal antibodies based enzyme-linked immunosorbent assay was used to detect H.Pylori specific antigen in stool samples.

Conditions

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Helicobacter Pylori Infection Acne Vulgaris

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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acne vlugaris group

Included recruited patients with acne vulgaris Intervention: Blood and stool samples collection

Blood and stool samples collection

Intervention Type OTHER

Collection of blood and stool samples from each participants for H.pylori antigen/ antibody detection

Control group

Included healthy participants Intervention: Blood and stool samples collection

Blood and stool samples collection

Intervention Type OTHER

Collection of blood and stool samples from each participants for H.pylori antigen/ antibody detection

Interventions

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Blood and stool samples collection

Collection of blood and stool samples from each participants for H.pylori antigen/ antibody detection

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Acne vulgaris patients
* Healthy volunteers (control)

Exclusion Criteria

* Patients with a history of drug intake that affects H. Pylori such as proton-pump inhibitors, clarithromycin, tetracyclines, amoxicillin or metronidazole within previous two weeks were excluded.
Minimum Eligible Age

12 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Sohag University

OTHER

Sponsor Role lead

Responsible Party

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Dina Ali

Resident physician, Department of Dermatology, Sohag Educational Hospital

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ramadan Saleh, MD

Role: STUDY_DIRECTOR

Sohag Faculty of Medicine

Locations

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Dermatology outpatient clinic, Sohag University Hospital

Sohag, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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HPAV001

Identifier Type: -

Identifier Source: org_study_id

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