Obstructive Sleep Apnoea in Adolescents With Thoracic Aortic Aneurysm

NCT ID: NCT03400319

Last Updated: 2021-05-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

174 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-07-05

Study Completion Date

2020-03-01

Brief Summary

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The objective of this prospective cohort study is to determine the prevalence of obstructive sleep apnoea (OSA) in patients with and without thoracic aortic aneurysm.

Detailed Description

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The objective of this prospective cohort study is to determine the prevalence of obstructive sleep apnoea (OSA) in patients with and without thoracic aortic aneurysm.

Conditions

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Thoracic Aortic Aneurysm Without Rupture Obstructive Sleep Apnea

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Thoracic Aortic Aneurysm

Patients with Thoracic Aortic Aneurysm: Women: at the level of the sinus of valsalva ≥39mm, or ascending aorta ≥42mm. Men: at the level of the sinus of valsalva ≥44mm, or ascending aorta ≥46mm.

No interventions assigned to this group

No Thoracic Aortic Aneurysm

Patients without Thoracic Aortic Aneurysm: Women: at the level of the sinus of valsalva \<39mm, or ascending aorta \<42mm. Men: at the level of the sinus of valsalva \<44mm, or ascending aorta \<46mm.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Age \> 18 years.
* Diagnosis of thoracic aortic aneurysm defined by the following parameters:

Women: at the level of the sinus of valsalva ≥39mm, or ascending aorta ≥42mm. (for controls: \<39mm and \<42mm respectively); Men: at the level of the sinus of valsalva ≥44mm, or ascending aorta ≥46mm. (for controls: \<44mm and \<46mm respectively)

Exclusion Criteria

* Patients on continuous positive airway pressure (CPAP) therapy for OSA at baseline.
* Patients with known central sleep apnoea.
* Patients on morphine or other opioid medication, heroin addiction, alcohol addiction.
* Patients with moderate or severe aortic regurgitation.
* Patients with moderate or severe aortic stenosis.
* Pregnant patients.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Zurich

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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University Hospital Zurich, Pulmonary Division

Zurich, , Switzerland

Site Status

Countries

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Switzerland

Other Identifiers

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KEK-ZH-Nr. 2014-0035 CTRL

Identifier Type: -

Identifier Source: org_study_id

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