3D MR Versus 3D CT for Glenohumeral Arthritis

NCT ID: NCT03379545

Last Updated: 2021-03-25

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

31 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-01-11

Study Completion Date

2020-06-05

Brief Summary

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This study aims to assess the efficacy of three-dimensional magnetic resonance (MR) compared to three-dimensional computed tomography (CT) imaging. This proposed study is a prospective, unrandomized, single-blinded, self-controlled, and single-armed diagnostic radiological evaluation study.

Detailed Description

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Conditions

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Arthritis Glenohumeral Osteoarthritis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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3D MR and 3D CT Imaging

All shoulder arthroplasty candidates with glenohumeral osteoarthritis will be receiving both 3D computed tomography (CT) and 3D non-contrast magnetic resonance (MR) imaging.

Group Type OTHER

3-dimensional (3D) magnetic resonance (MR) imaging

Intervention Type DIAGNOSTIC_TEST

MRI is performed using 3T scanners with a dedicated 16-channel shoulder array coils. The MRI sequences include 3-mm slice thickness and 0.5-mm gap width with a field of view of 14 or 15 cm. There were 6 diagnostic sequences with axial, coronal, and sagittal proton density weighting as well as coronal T2 with frequency selective fat suppression and sagittal T1 images.

3D computed tomography (CT) imaging

Intervention Type DIAGNOSTIC_TEST

The CT protocol consists of 3-mm axial images of the glenoid reconstructed into 1-mm sagittal and coronal 2D reconstructions using the following parameters: 120 kV, 280 mA, and pitch of 0.9. The CT data were also used to produce a 3D reconstruction of each glenoid.

Interventions

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3-dimensional (3D) magnetic resonance (MR) imaging

MRI is performed using 3T scanners with a dedicated 16-channel shoulder array coils. The MRI sequences include 3-mm slice thickness and 0.5-mm gap width with a field of view of 14 or 15 cm. There were 6 diagnostic sequences with axial, coronal, and sagittal proton density weighting as well as coronal T2 with frequency selective fat suppression and sagittal T1 images.

Intervention Type DIAGNOSTIC_TEST

3D computed tomography (CT) imaging

The CT protocol consists of 3-mm axial images of the glenoid reconstructed into 1-mm sagittal and coronal 2D reconstructions using the following parameters: 120 kV, 280 mA, and pitch of 0.9. The CT data were also used to produce a 3D reconstruction of each glenoid.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Patients suffering from glenohumeral OA;
* Radiographic evidence of severe glenoid erosion;
* Indication for TSA based on clinical exam;
* Patient is willing to participate by complying with pre-operative visit requirements;
* Patient is willing and able to review and sign a study informed consent form.

Exclusion Criteria

* Prior arthroplasty at the affected shoulder;
* Patients with inflammatory arthritis;
* Patients with post-capsulorrhaphy arthritis;
* Patients with post-traumatic arthritis;
* Patients with rotator cuff tear arthropathy;
* Patients exhibiting a lack of physical or mental ability to perform or comply with the study procedures;
* Patients who are pregnant;
* Patients with implanted medical devices that are contraindicated to exposure up to a 3.0-tesla magnetic field.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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NYU Langone Health

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Joseph D Zuckerman, MD

Role: PRINCIPAL_INVESTIGATOR

NYU Langone Health

Locations

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New York University School of Medicine

New York, New York, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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17-00500

Identifier Type: -

Identifier Source: org_study_id

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