Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
40 participants
INTERVENTIONAL
2017-11-13
2018-05-05
Brief Summary
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This study is designed to compare the optic nerve sheath diameter using 10cc of nomal saline of different speed (3cc/sec vs. 1cc/sec).
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Detailed Description
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According to previous study, injection of different volume of local anesthetics (1.0 ml/kg vs. 1.5 ml/kg) during caudal anesthesia, high volume of local anesthetics resulted in significant increase of intracranial pressure (ICP). Increase of ICP can reduce regional cerebral flow and oxygen saturation causing the safety of patients. In addition, increase of ICP can result in headache, syncope, and transient loss of visual acuity.
Although it is very invasive method, ICP can be measured directly at the brain parenchyme. Among methods to measure the ICP indirectly, measurement of optic nerve sheath diameter using ultrasound is known to reflect the degree of ICP. It is reported that optic nerve sheath diameter increases when higher volume of medication is injected during epidural anesthesia.
This study is designed to compare the optic nerve sheath diameter using 10cc of nomal saline of different speed (3cc/sec vs. 1cc/sec).
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Rapid speed of injection
Rapid speed of injection (3cc/sec) during thoracic epidurography thoracic epidural catheterization
thoracic epidural catheterization
thoracic epidural catheterization with different speed of injection
Slow speed of injection
Slow speed of injection (1cc/sec) during thoracic epidurography thoracic epidural catheterization
thoracic epidural catheterization
thoracic epidural catheterization with different speed of injection
Interventions
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thoracic epidural catheterization
thoracic epidural catheterization with different speed of injection
Eligibility Criteria
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Inclusion Criteria
* liver cancer
* stomach cancer
* pancreas cancer
Exclusion Criteria
* infection
* previous spine fusion at thoracic level
* previous brain surgery
20 Years
80 Years
ALL
No
Sponsors
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Keimyung University Dongsan Medical Center
OTHER
Responsible Party
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Ji Hee Hong
Professor
Principal Investigators
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Ji Hee Hong, PhD
Role: PRINCIPAL_INVESTIGATOR
Keimyung University
Locations
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Ji Hee Hong
Daegu, , South Korea
Countries
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References
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Hong JH, Jung SW, Park JH. The Effect of Speed of Normal Saline Injection on Optic Nerve Sheath Diameter in Thoracic Epidural Anesthesia. Pain Physician. 2019 Jul;22(4):E325-E332.
Other Identifiers
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2017-08-017
Identifier Type: -
Identifier Source: org_study_id
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