High Versus Low Frequency rTMS on Motor Dysfunction in PD
NCT ID: NCT03342846
Last Updated: 2020-09-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
40 participants
INTERVENTIONAL
2017-08-20
2018-02-25
Brief Summary
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The patients were randomly assigned into two groups; the first group received 1Hz and the 2nd one received 20 Hz rTMS daily for 10 days 5 sessions every week. The doctors who assess the patients clinically is blind for the frequency of rTMS, also patients don't know which type of stimulation they received. The patients were followed up before and after the 10 sessions and one month later.
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Detailed Description
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The patients were randomly assigned into two groups; the first group received 1Hz and the 2nd one received 20 Hz rTMS daily for 10 days 5 sessions every week and 2 days off per week. The doctors who assess the patients clinically is blind for the frequency of rTMS, also patients don't know which type of stimulation they received. The patients were followed up before and after the 10 sessions and one month later.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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High Frequency rTMS in PD
The first group received 20 Hz rTMS on M1 daily for 10 days 5 sessions every week.
rTMS
the first group received 20 Hz and the 2nd group received 1 Hz rTMS daily for 10 days 5 sessions every week on M1.
Low Frequency rTMS in PD
The second group received 1 Hz rTMS on M1 daily for 10 days 5 sessions every week.
rTMS
the first group received 20 Hz and the 2nd group received 1 Hz rTMS daily for 10 days 5 sessions every week on M1.
Interventions
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rTMS
the first group received 20 Hz and the 2nd group received 1 Hz rTMS daily for 10 days 5 sessions every week on M1.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* History of repeated cerebrovascular strokes
* History of defined encephalitis
* Oculogyric crisis, supra nuclear gaze palsy.
* Family history of more than one relative
* severe dementia, MMSE \< 23, severe depression
* Cerebellar signs
* Babiniski sign
* Hydrocephalus or intracranial lesion on neuroimaging
* Patients with intracranial on neuroimaging
* Patients with intracranial metallic device or pacemaker
* Patients who were unable to give informed consent because of severe anesthesia, or cognitive deficit
50 Years
80 Years
ALL
No
Sponsors
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Assiut University
OTHER
Responsible Party
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Eman M. Khedr
Professor
Principal Investigators
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eman M Khedr, MD
Role: PRINCIPAL_INVESTIGATOR
Professor of Neurology, Faculty of Medicine, Assiut University
Locations
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Eman Khedr
Asyut, , Egypt
Countries
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Other Identifiers
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High versus low TMS in PD.
Identifier Type: -
Identifier Source: org_study_id
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