Berlin-Brandenburg Pregnancy Cohort

NCT ID: NCT03313024

Last Updated: 2018-08-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1580 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-09-26

Study Completion Date

2027-10-31

Brief Summary

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This study will investigate the interplay of different immune cells and placental cells as well as their potential for the development of pregnancy complications. In particular, the translation of the uteroplacental syndrome into a maternal syndrome, considered in the multifactorial pregnancy disorder preeclampsia, will be investigated. Immune cell subtypes are causally involved in the formation and translation of preeclampsia by inducing an endothelial dysfunction which leads to cardiovascular damage.

Detailed Description

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Conditions

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Preeclampsia Pregnancy Complications Diabetes Mellitus in Pregnancy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* healthy pregnant women after giving informed consent
* pregnant with diagnosis of preeclampsia, gestational hypertension or gestational diabetes

Exclusion Criteria

* infections
* alcohol and drug abuse
* manifest and chronic diseases
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Charite University, Berlin, Germany

OTHER

Sponsor Role lead

Responsible Party

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Florian Herse

PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Experimental and Clinical Research Center (ECRC)

Berlin, , Germany

Site Status RECRUITING

Countries

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Germany

Central Contacts

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Florian Herse, PhD

Role: CONTACT

+49 30 450 540 434

Facility Contacts

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Florian Herse, PhD

Role: primary

+49 30 450 540 434

Other Identifiers

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BBPC

Identifier Type: -

Identifier Source: org_study_id

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