Immunological and Cardiovascular Phenotyping of Oocyte-donation Pregnancies

NCT ID: NCT04731012

Last Updated: 2021-01-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-01-01

Study Completion Date

2025-12-01

Brief Summary

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The investigators conduct a study to evaluate the underlying causes of preeclampsia in oocyte-donation pregnancies.

Detailed Description

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A detailed medical history, questionnaires as well as blood, urine and placental samples will be used to analyse several factors leading to the high risk of preeclampsia in oocyte-donation pregnancies.

Conditions

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Preeclampsia Oocyte-donation Pregnancies

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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healthy oocyte-donation pregnancy

healthy pregnancy

No interventions assigned to this group

preeclamptic oocyte-donation pregnancy

preeclampsia

No interventions assigned to this group

healthy IVF or ICSI pregnancy

healthy pregnancy

No interventions assigned to this group

preeclamptic IVF or ICSI pregnancy

preeclampsia

No interventions assigned to this group

healthy spontaneous conception pregnancy

healthy pregnancy

No interventions assigned to this group

preeclamptic spontaneous conception pregnancy

preeclampsia

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* pregnancy

Exclusion Criteria

* severe auto immune disorders
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Charite University, Berlin, Germany

OTHER

Sponsor Role lead

Responsible Party

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Florian Herse

Doctor of Science

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Experimental and Clinical Research Center (ECRC)

Berlin, , Germany

Site Status RECRUITING

Countries

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Germany

Central Contacts

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Florian Herse, DSc

Role: CONTACT

Phone: +49 30 450 540 434

Email: [email protected]

Judith Altmann, MD

Role: CONTACT

Email: [email protected]

Facility Contacts

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Florian Herse, PhD

Role: primary

Other Identifiers

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ED-S

Identifier Type: -

Identifier Source: org_study_id