Comparing Human Albumin Versus Hydroxyethylstarch in Renal Transplant Recipients

NCT ID: NCT03306914

Last Updated: 2020-01-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-10-15

Study Completion Date

2019-02-01

Brief Summary

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In this study we try to review the possible effects when using modern hydroxyethylstarch solutions 6 % versus albumin 5% during living donor renal transplantation.

Detailed Description

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Conditions

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Anesthesia Morbidity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Participants

Study Groups

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Albumin group

Albumin resuscitation Albumin 5%

Group Type ACTIVE_COMPARATOR

Albumin resuscitation

Intervention Type OTHER

Albumin 5% is used as the intra-operative colloid

Albumin 5%

Intervention Type DRUG

Infusion of Albumin 5% intra-operatively

Hydroxyethylstarch group

Hydroxyethylstarch resuscitation Hydroxyethylstarch 6%

Group Type EXPERIMENTAL

Hydroxyethylstarch resuscitation

Intervention Type OTHER

Hydroxyethyl starch 6% is used as the intra-operative colloid

Hydroxyethylstarch 6%

Intervention Type DRUG

Infusion of Hydroxyethylstarch 6% intra-operatively

Interventions

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Albumin resuscitation

Albumin 5% is used as the intra-operative colloid

Intervention Type OTHER

Hydroxyethylstarch resuscitation

Hydroxyethyl starch 6% is used as the intra-operative colloid

Intervention Type OTHER

Albumin 5%

Infusion of Albumin 5% intra-operatively

Intervention Type DRUG

Hydroxyethylstarch 6%

Infusion of Hydroxyethylstarch 6% intra-operatively

Intervention Type DRUG

Other Intervention Names

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Albumin Tetraspan

Eligibility Criteria

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Inclusion Criteria

* end stage renal disease, for living donor renal transplantation

Exclusion Criteria

* severe cardiac or hepatic dysfunction, re-transplantation, coagulopathy
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Ahmed Kareem

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ahmed Kareem

Role: STUDY_DIRECTOR

Kasr Al-Ainy Hospiral, Cairo University

Locations

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Cairo University

Cairo, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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Albumin versus starch

Identifier Type: -

Identifier Source: org_study_id

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